Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.77 |
| ▸ | RAB9A | P51151 | 5/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | HTT | P42858 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | CASP3 | P42574 | 1/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.70 |
| ▸ | AOC3 | Q16853 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL972254 | 0.88 | AOC3 (0.74) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL7079364 | 0.88 | AOC3 (0.59) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL3405939 | 0.87 | RAB9A (0.77) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL4871628 | 0.87 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL16242472 | 0.85 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL16556647 | 0.84 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL971401 | 0.84 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL973243 | 0.84 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL972558 | 0.83 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL6799338 | 0.83 | RAB9A (0.70) | NPC1RAB9ASMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | NPC1 64/4885RAB9A 3707/4885SMN1; SMN2 2504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.