Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554436 | 0.88 | ALDH1A1 (0.51) | KMT2AGAAHSD17B10MEN1CYP1A2 | |
| SCHEMBL10551215 | 0.80 | GAA (0.49) | KMT2AGAAHSD17B10MEN1CYP1A2 | |
| SCHEMBL4124065 | 0.77 | HTT (0.46) | KMT2AHSD17B10MEN1ALDH1A1MAPT | |
| SCHEMBL10553572 | 0.76 | ALDH1A1 (0.47) | KMT2AGAAHSD17B10MEN1CYP1A2 | |
| SCHEMBL10556333 | 0.75 | GAA (0.51) | KMT2AGAAHSD17B10MEN1CYP1A2 | |
| SCHEMBL29538871 | 0.74 | KMT2A (0.42) | KMT2AGAAHSD17B10MEN1CYP1A2 | |
| SCHEMBL10550802 | 0.74 | NPC1 (0.52) | KMT2AGAAHSD17B10MEN1CYP1A2 | |
| Oxalic Acid SCHEMBL10558687 | 0.73 | KDM4E (0.48) | KMT2AGAAHSD17B10MEN1ALDH1A1 | |
| SCHEMBL10551047 | 0.72 | GAA (0.51) | KMT2AGAAHSD17B10MEN1CYP1A2 | |
| SCHEMBL13089996 | 0.71 | CBX7 (0.47) | KMT2AMEN1CYP2C9ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4879293-A | NERVOUS SYSTEM AND PSYCHOSOMATIC DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| US-4788191-A | ANTIANXIETY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-29 | — | — | US | disclosed |
| US-4590189-A | ANTIANXIETY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-05-20 | — | — | US | disclosed |
| EP-0091241-A2 | Condensed pyrrolinone derivatives, and their production | Takeda Chemical Industries, Ltd. (JP) | 1983-10-12 | — | — | EP | disclosed |