Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBX7 | O95931 | 2/20 | 0.47 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.47 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.47 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 8/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10553572 | 0.91 | ALDH1A1 (0.47) | ACHEKDM4EALDH1A1MAPTCYP2C9 | |
| SCHEMBL10561025 | 0.82 | RAB9A (0.53) | ACHEALDH1A1MAPTCYP2C9CYP2C19 | |
| SCHEMBL10554436 | 0.80 | ALDH1A1 (0.51) | ACHEKDM4EALDH1A1MAPTHIF1A | |
| SCHEMBL10552491 | 0.80 | RAB9A (0.56) | KDM4EALDH1A1CYP2C9CYP2C19MEN1 | |
| SCHEMBL10555676 | 0.78 | TSHR (0.48) | ACHEKDM4EALDH1A1MAPTCYP2C9 | |
| Oxalic Acid SCHEMBL10558687 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10551047 | 0.76 | GAA (0.51) | KDM4EALDH1A1MAPTCYP2C9MEN1 | |
| SCHEMBL10552800 | 0.75 | KMT2A (0.46) | L3MBTL1KDM4EALDH1A1MAPTCYP2C9 | |
| SCHEMBL10551143 | 0.72 | ALDH1A1 (0.50) | ACHEL3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL10550805 | 0.71 | KMT2A (0.54) | KDM4EALDH1A1MAPTCYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243776-A1 | Substituted piperidines and their use for the treatment of diseases related to the histamine H3 receptor | High Point Pharmaceuticals, LLC (US) | 2010-10-27 | — | — | EP | disclosed |