6-Aminonicotinamide

6-Aminonicotinamide

SCHEMBL105510

NC(=O)c1ccc(N)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NNMT P40261 4/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
MKNK1 Q9BUB5 2/20 0.71
MKNK2 Q9HBH9 2/20 0.71
GABRP O00591 2/20 0.69
GABRD O14764 2/20 0.69
GABRA1 P14867 2/20 0.69
GABRB1 P18505 2/20 0.69
GABRG2 P18507 2/20 0.69
GABRB3 P28472 2/20 0.69
GABRA5 P31644 2/20 0.69
GABRA3 P34903 2/20 0.69
GABRA2 P47869 2/20 0.69
GABRB2 P47870 2/20 0.69
GABRA4 P48169 2/20 0.69
GABRE P78334 2/20 0.69
GABRA6 Q16445 2/20 0.69
GABRG1 Q8N1C3 2/20 0.69
GABRG3 Q99928 2/20 0.69
GABRQ Q9UN88 2/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
6-Aminonicotinamide SCHEMBL29780372 0.92 NNMT (0.85) NNMTSMN1; SMN2MKNK1MKNK2GABRP
6-Aminonicotinamide SCHEMBL25343859 0.92 NNMT (0.85) NNMTSMN1; SMN2MKNK1MKNK2GABRP
6-Aminonicotinamide SCHEMBL27680604 0.90 NNMT (0.81) NNMTSMN1; SMN2MKNK1MKNK2GABRP
6-Aminonicotinamide SCHEMBL11582983 0.90 NNMT (0.81) NNMTSMN1; SMN2MKNK1MKNK2GABRP
6-Aminonicotinamide SCHEMBL10544808 0.90 NNMT (0.81) NNMTSMN1; SMN2MKNK1MKNK2GABRP
6-Aminonicotinamide SCHEMBL10544812 0.90 NNMT (0.81) NNMTSMN1; SMN2MKNK1MKNK2GABRP
6-Aminonicotinamide SCHEMBL10860974 0.89 NNMT (0.79) NNMTSMN1; SMN2MKNK1MKNK2GABRP
6-Aminonicotinamide SCHEMBL11268491 0.87 NNMT (0.76) NNMTSMN1; SMN2MKNK1MKNK2GABRP
SCHEMBL16853374 0.84 GABRP (0.72) NNMTSMN1; SMN2MKNK1MKNK2GABRP
Carbamic Acid SCHEMBL9949749 0.83 GABRP (0.92) NNMTSMN1; SMN2MKNK1MKNK2GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 23298 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094660-A Composition in the form of an oil-in-water emulsion 2026-05-26 CN claimed
EP-4687829-A1 COMPOSITION FOR CARING FOR KERATIN MATERIALS L'OREAL (FR) 2026-02-11 EP claimed
US-20250381116-A1 SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME OREAL (FR) 2025-12-18 US claimed
US-20250360216-A1 CONTROLLED DRUG RELEASE FROM ELECTROSPUN FIBERS RENSSELAER POLYTECHNIC INSTITUTE (US) 2025-11-27 US claimed
EP-4561704-A2 USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER The University Of Vermont (US) 2025-06-04 EP claimed
US-20250161201-A1 COSMETIC COMPOSITION THE BOOTS COMPANY PLC (GB) 2025-05-22 US claimed
WO-2025091239-A1 COMPOSITION IN THE FORM OF OIL-IN-WATER EMULSION L'OREAL (FR) 2025-05-08 WO claimed
WO-2025091220-A2 COMPOSITION IN THE FORM OF OIL-IN-WATER EMULSION L'OREAL (FR) 2025-05-08 WO claimed
EP-4543408-A1 SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME L'OREAL (FR) 2025-04-30 EP claimed
CN-119654151-A Composition for caring skin 莱雅公司 2025-03-18 CN claimed
US-5094740-A TWO-DIMENSIONAL ELECTROPHORETIC SEPARATION OF CARBOHYDRATES GLYCOMED, INC. (US) 1992-03-10 US claimed
WO-1991012276-A1 ELECTRO-BLOTTING OF ELECTROPHORETICALLY RESOLVED FLUORESCENT-LABELED SACCHARIDES AND DETECTION OF ACTIVE STRUCTURES WITH PROTEIN PROBES GLYCOMED INCORPORATED (US) 1991-08-22 WO claimed
WO-1991012275-A1 TWO-DIMENSIONAL ELECTROPHORETIC SEPARATION OF CARBOHYDRATES GLYCOMED INCORPORATED (US) 1991-08-22 WO claimed
US-4588525-A Prodrug compounds for dermal application MOLECULAR BIOSYSTEMS, INC. (US) 1986-05-13 US claimed
EP-0071045-A1 Trialkylsilyl-6-aminonicotinamides International Plant Research Institute (US) 1983-02-09 EP claimed
US-4316902-A Therapeutic compositions and vehicles for topical pharmaceuticals YU RUEY J 1982-02-23 US claimed
US-4284630-A Stabilized water-in-oil emulsions YU RUEY J 1981-08-18 US claimed
US-4252796-A ALUMINUM COMPOUNDS, ANTIINFLAMMATORY AGENTS YU RUEY J 1981-02-24 US claimed
US-4251536-A Rodenticides comprising 6-aminonicotinamide or 6-aminonicotinohydroxamic acid JOHNSON WILLARD J 1981-02-17 US claimed
US-4067975-A Treatment of psoriasis with 6-aminonicotinamide and thionicotinamide YU RUEY J 1978-01-10 US claimed