6-Aminonicotinamide

6-Aminonicotinamide

SCHEMBL27680604

ClOCl.NC(=O)c1ccc(N)nc1.[SeH2]

nearest known ligand 0.81

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NNMT P40261 4/20 0.81
SMN1; SMN2 Q16637 1/20 0.81
MKNK1 Q9BUB5 2/20 0.61
MKNK2 Q9HBH9 2/20 0.61
GABRP O00591 2/20 0.58
GABRD O14764 2/20 0.58
GABRA1 P14867 2/20 0.58
GABRB1 P18505 2/20 0.58
GABRG2 P18507 2/20 0.58
GABRB3 P28472 2/20 0.58
GABRA5 P31644 2/20 0.58
GABRA3 P34903 2/20 0.58
GABRA2 P47869 2/20 0.58
GABRB2 P47870 2/20 0.58
GABRA4 P48169 2/20 0.58
GABRE P78334 2/20 0.58
GABRA6 Q16445 2/20 0.58
GABRG1 Q8N1C3 2/20 0.58
GABRG3 Q99928 2/20 0.58
GABRQ Q9UN88 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
6-Aminonicotinamide SCHEMBL10544812 0.96 NNMT (0.81) NNMTSMN1; SMN2MKNK1MKNK2GABRP
6-Aminonicotinamide SCHEMBL105510 0.90 NNMT (1.00) NNMTSMN1; SMN2MKNK1MKNK2GABRP
6-Aminonicotinamide SCHEMBL25343859 0.87 NNMT (0.85) NNMTSMN1; SMN2MKNK1MKNK2GABRP
6-Aminonicotinamide SCHEMBL10544808 0.85 NNMT (0.81) NNMTSMN1; SMN2MKNK1MKNK2GABRP
6-Aminonicotinamide SCHEMBL29780372 0.83 NNMT (0.85) NNMTSMN1; SMN2MKNK1MKNK2GABRP
6-Aminonicotinamide SCHEMBL11582983 0.81 NNMT (0.81) NNMTSMN1; SMN2MKNK1MKNK2GABRP
6-Aminonicotinamide SCHEMBL10860974 0.80 NNMT (0.79) NNMTSMN1; SMN2MKNK1MKNK2GABRP
6-Aminonicotinamide SCHEMBL11268491 0.79 NNMT (0.76) NNMTSMN1; SMN2MKNK1MKNK2GABRP
SCHEMBL5238352 0.76 GABRP (0.67) NNMTSMN1; SMN2MKNK1MKNK2GABRP
SCHEMBL16853374 0.76 GABRP (0.72) NNMTSMN1; SMN2MKNK1MKNK2GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-86107767-A NOVEL ORGANIC SELENIUM COMPOUNDS 1987-08-05 CN disclosed