Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413407 | 0.87 | HSD17B10 (0.33) | KDM4EALDH1A1L3MBTL1HSD17B10MAPT | |
| SCHEMBL10549582 | 0.82 | POLB (0.53) | KDM4EALDH1A1L3MBTL1POLBHSD17B10 | |
| SCHEMBL10547616 | 0.81 | GAPDH (0.40) | KDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL10548246 | 0.80 | GAPDH (0.40) | KDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL10547546 | 0.80 | NR1I2 (0.45) | KDM4EALDH1A1L3MBTL1POLBHSD17B10 | |
| SCHEMBL10544574 | 0.80 | ALDH1A1 (0.37) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL10544583 | 0.80 | ALDH1A1 (0.37) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL10550552 | 0.80 | NPC1 (0.41) | ALDH1A1L3MBTL1POLBHSD17B10MEN1 | |
| SCHEMBL10545935 | 0.78 | — | — | |
| SCHEMBL10546722 | 0.78 | ESR1 (0.40) | KDM4EALDH1A1L3MBTL1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831130-A | β-lactam antibacterial agents | HOFFMANN-LA ROCHE INC. (US) | 1989-05-16 | — | — | US | disclosed |