Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 10/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10551844 | 1.00 | KMT2A (0.42) | KMT2AMEN1KLK7LMNASMN1; SMN2 | |
| SCHEMBL10547432 | 0.91 | KMT2A (0.42) | KMT2AMEN1KLK7LMNASMN1; SMN2 | |
| SCHEMBL10545815 | 0.90 | KMT2A (0.42) | KMT2AMEN1KLK7LMNASMN1; SMN2 | |
| SCHEMBL10414813 | 0.85 | CYP3A4 (0.31) | KMT2AMAPK1ALDH1A1 | |
| SCHEMBL10414814 | 0.85 | CYP3A4 (0.31) | KMT2AMAPK1ALDH1A1 | |
| SCHEMBL10547616 | 0.84 | GAPDH (0.40) | KMT2AALDH1A1 | |
| SCHEMBL10548246 | 0.83 | GAPDH (0.40) | KMT2AALDH1A1 | |
| SCHEMBL10546713 | 0.81 | CASP1 (0.38) | — | |
| SCHEMBL10550552 | 0.79 | NPC1 (0.41) | KMT2AMEN1SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL10548985 | 0.79 | LMNA (0.38) | KMT2AMEN1LMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831130-A | β-lactam antibacterial agents | HOFFMANN-LA ROCHE INC. (US) | 1989-05-16 | — | — | US | disclosed |