Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 12/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8155546 | 0.88 | MAOA (0.58) | ERAP1NPC1RAB9ACYSLTR1 | |
| SCHEMBL10546844 | 0.85 | ERAP1 (0.53) | ERAP1NPC1RAB9ACYSLTR1AR | |
| SCHEMBL10989066 | 0.82 | CYSLTR1 (0.71) | ERAP1NPC1RAB9ACYSLTR1CYP1A1 | |
| SCHEMBL10549952 | 0.82 | L3MBTL1 (0.52) | ERAP1NPC1RAB9ACYSLTR1CYP1A2 | |
| SCHEMBL10551657 | 0.82 | NTRK1 (0.57) | ERAP1NPC1RAB9ACYSLTR1CYP1A1 | |
| SCHEMBL10547237 | 0.81 | MAOA (0.56) | ERAP1NPC1CYSLTR1AR | |
| Hydrochloric Acid SCHEMBL10991396 | 0.81 | CYSLTR1 (0.70) | ERAP1NPC1RAB9ACYSLTR1CYP1A1 | |
| SCHEMBL5123750 | 0.78 | MCL1 (0.52) | ERAP1NPC1RAB9ACYSLTR1 | |
| SCHEMBL27974835 | 0.78 | MAOA (0.50) | ERAP1 | |
| SCHEMBL10549752 | 0.78 | PTGER1 (0.55) | ERAP1NPC1RAB9ACYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882340-A | INHIBITS REFLECTIVE CONTRACTION OF URINARY BLADDER | TANABE SEIYAKU CO., LTD. (JP) | 1989-11-21 | — | — | US | disclosed |
| US-4829067-A | INHIBITORS OF REFLECTIVE CONTRACTION OF BLADDER | TANABE SEIYAKU CO., LTD. (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0306226-A2 | A benzofuran derivative and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1989-03-08 | — | — | EP | disclosed |
| EP-0270342-A2 | A benzo-furan (or -thiophene) derivative and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |