Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.55 |
| ▸ | ERAP1 | Q9NZ08 | 8/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.45 |
| ▸ | TUBB8B | A6NNZ2 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224507 | 0.87 | ERAP1 (0.53) | PTGER1ERAP1GPR35NPC1RAB9A | |
| SCHEMBL3215517 | 0.85 | PTGER1 (0.47) | PTGER1ERAP1NPC1KDM4EALDH1A1 | |
| SCHEMBL5123749 | 0.83 | NPC1 (0.51) | PTGER1GPR35NPC1RAB9AKDM4E | |
| SCHEMBL8155546 | 0.80 | MAOA (0.58) | ERAP1NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL5124786 | 0.78 | ALDH1A1 (0.49) | GPR35NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL10552149 | 0.78 | ERAP1 (0.66) | ERAP1NPC1RAB9ACYSLTR1 | |
| SCHEMBL10553934 | 0.77 | MAOA (0.53) | GPR35NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL14104632 | 0.77 | TUBB8B (0.43) | PTGER1KDM4EALDH1A1TUBB8BEGFR | |
| SCHEMBL3224946 | 0.76 | PTGER1 (0.55) | PTGER1ERAP1NPC1RAB9AESR1 | |
| SCHEMBL2956591 | 0.75 | DHODH (0.61) | NPC1RAB9AKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882340-A | INHIBITS REFLECTIVE CONTRACTION OF URINARY BLADDER | TANABE SEIYAKU CO., LTD. (JP) | 1989-11-21 | — | — | US | disclosed |
| US-4829067-A | INHIBITORS OF REFLECTIVE CONTRACTION OF BLADDER | TANABE SEIYAKU CO., LTD. (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0306226-A2 | A benzofuran derivative and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1989-03-08 | — | — | EP | disclosed |
| EP-0270342-A2 | A benzo-furan (or -thiophene) derivative and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |