Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14663931 | 0.74 | RAB9A (0.52) | PGRNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL16155526 | 0.73 | PGR (0.51) | PGRNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL10651704 | 0.72 | ALDH1A1 (0.48) | PGRNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL10555272 | 0.71 | SMN1; SMN2 (0.42) | PGRKDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL11988993 | 0.71 | NPC1 (0.46) | PGRNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL10556389 | 0.71 | KDM4E (0.43) | PGRNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL10553937 | 0.70 | PGR (0.44) | PGRNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL30667104 | 0.70 | RAB9A (0.52) | PGRNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL29127949 | 0.70 | RAB9A (0.52) | PGRNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL6088862 | 0.69 | KDM4E (0.56) | PGRNPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4879293-A | NERVOUS SYSTEM AND PSYCHOSOMATIC DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| US-4788191-A | ANTIANXIETY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-29 | — | — | US | disclosed |
| US-4590189-A | ANTIANXIETY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-05-20 | — | — | US | disclosed |
| EP-0091241-A2 | Condensed pyrrolinone derivatives, and their production | Takeda Chemical Industries, Ltd. (JP) | 1983-10-12 | — | — | EP | disclosed |