SCHEMBL10554190

SCHEMBL10554190

Cc1cc(Cl)ccc1-c1ccc(C(=O)C=O)cc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.41
SRD5A1 P18405 1/20 0.38
SRD5A2 P31213 1/20 0.38
NOTUM Q6P988 2/20 0.38
MAPK1 P28482 2/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
MYC P01106 1/20 0.37
NR4A1 P22736 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAPT P10636 2/20 0.37
HPGD P15428 2/20 0.37
ALOX12 P18054 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
PLA2G1B P04054 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7568030 0.79 TAS1R3 (0.47) MAPK1MAOAMAOBALDH1A1TDP1
Water SCHEMBL11074038 0.77 TAS1R3 (0.46) MAPK1MAOAMAOBALDH1A1TDP1
SCHEMBL3627481 0.77 ESR2 (0.51) MAPK1CES2CES1ALDH1A1TDP1
SCHEMBL9501048 0.77 SRD5A2 (0.38) SRD5A1SRD5A2MAPK1CES2CES1
SCHEMBL1483722 0.76 SMN1; SMN2 (0.52) MAPK1CES2CES1ALDH1A1TDP1
SCHEMBL29719717 0.75 NOTUM (0.53) GRM2NOTUM
SCHEMBL29957159 0.75 PIM1 (0.44) MAPK1CES2CES1MAOAMAOB
SCHEMBL2866317 0.75 TDP1 (0.46) SRD5A2MAPK1CES2CES1ALDH1A1
SCHEMBL8984336 0.74 TDP1 (0.44) SRD5A2MAPK1CES2CES1ALDH1A1
Water SCHEMBL11073909 0.74 HPGD (0.47) MAPK1ALDH1A1TDP1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4866154-A Aromatic polyester from substituted hydroquinone and biphenyl dicarboxylic acid BAYER AKTIENGESELLSCHAFT (DE) 1989-09-12 US disclosed