Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554190 | 0.77 | GRM2 (0.41) | SRD5A2SRD5A1ALDH1A1MAPK1TDP1 | |
| SCHEMBL20599056 | 0.75 | S100A4 (0.46) | ALDH1A1TDP1TP53CES1ALOX15 | |
| SCHEMBL1483257 | 0.75 | MAOB (0.49) | ALDH1A1MAPK1TDP1NPC1RAB9A | |
| SCHEMBL2866317 | 0.75 | TDP1 (0.46) | SRD5A2ALDH1A1MAPK1TDP1NPC1 | |
| SCHEMBL8984336 | 0.74 | TDP1 (0.44) | SRD5A2ALDH1A1MAPK1TDP1NPC1 | |
| SCHEMBL1673734 | 0.73 | MAPK1 (0.58) | SRD5A2ALDH1A1MAPK1TDP1CES2 | |
| SCHEMBL9501454 | 0.73 | RAB9A (0.48) | SRD5A2SRD5A1RAB9ATP53TSHR | |
| SCHEMBL11152327 | 0.72 | TDP1 (0.43) | SRD5A2ALDH1A1MAPK1TDP1NPC1 | |
| SCHEMBL10881838 | 0.72 | VCAM1 (0.46) | ALDH1A1MAPK1NPC1RAB9ATSHR | |
| Water SCHEMBL10353718 | 0.72 | MAPK1 (0.56) | SRD5A2ALDH1A1MAPK1TDP1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322788-B1 | MELT-PROCESSABLE AROMATIC POLYESTERAMIDES HAVING REPEATING 2,2'-SUBSTITUTED BIPHENYLENE RADICALS | POLAROID CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| EP-0322788-A2 | Melt-processable aromatic polyesteramides having repeating 2,2'-substituted biphenylene radicals | POLAROID CORPORATION (US) | 1989-07-05 | — | — | EP | disclosed |
| US-4843141-A | HIGH STREENGTH FILMS AND FIBERS | POLAROID CORPORATION, PATENT DEPARTMENT (US) | 1989-06-27 | — | — | US | disclosed |
| US-4608429-A | Low-melting aromatic polyesters with repeating 2,2'-substituted-biphenylene radicals | POLAROID CORPORATION, PATENT DEPT. (US) | 1986-08-26 | — | — | US | disclosed |