Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL408187 | 0.85 | ALDH1A1 (0.47) | MAPTCYP17A1CYP3A4PIK3CDPIK3CA | |
| Hydrochloric Acid SCHEMBL28121739 | 0.83 | ALDH1A1 (0.45) | MAPTCYP17A1CYP3A4MAOBPIK3CD | |
| SCHEMBL27876154 | 0.81 | LTA4H (0.55) | LTA4HLMNAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL8873188 | 0.81 | LTA4H (0.56) | LTA4HCYP11B1CYP11B2CYP3A4CYP19A1 | |
| SCHEMBL498377 | 0.78 | ALDH1A1 (0.56) | MAPTCYP17A1LMNAMAOBPIK3CD | |
| SCHEMBL3890418 | 0.73 | MAOB (0.61) | MAPTMAOBALDH1A1 | |
| SCHEMBL28931548 | 0.73 | ALDH1A1 (0.44) | MAPTCYP17A1LMNAMAOBPIK3CD | |
| SCHEMBL14331359 | 0.73 | LTA4H (0.45) | LTA4HMAPTCYP17A1LMNAMAOB | |
| SCHEMBL10271093 | 0.73 | SMN1; SMN2 (0.45) | MAPTCYP17A1LMNAMAOBPIK3CD | |
| SCHEMBL122100 | 0.73 | ALDH1A1 (0.44) | MAPTCYP17A1LMNAMAOBPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886822-A | SIDE EFFECT REDUCTION | KOWA COMPANY, LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0286979-A1 | Substituted anilide derivatives | KOWA COMPANY, LTD. (JP) | 1988-10-19 | — | — | EP | disclosed |