Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10553070 | 0.83 | HTR7 (0.48) | HTR7CHRM3CHRM2CHRM1DRD2 | |
| Hydrochloric Acid SCHEMBL10549381 | 0.82 | HTR7 (0.47) | HTR7CHRM3CHRM2CHRM1DRD2 | |
| SCHEMBL9727223 | 0.81 | HTR7 (0.71) | HTR7CHRM3CHRM2CHRM1HTR1A | |
| SCHEMBL11072209 | 0.80 | HTR7 (0.69) | HTR7CHRM3CHRM2CHRM1HTR1A | |
| SCHEMBL7932835 | 0.80 | HTR7 (0.69) | HTR7CHRM3CHRM2CHRM1HTR1A | |
| Hydrochloric Acid SCHEMBL7926756 | 0.79 | HTR7 (0.67) | HTR7CHRM3CHRM2CHRM1HTR1A | |
| SCHEMBL13533347 | 0.78 | HTR7 (0.66) | HTR7CHRM3CHRM2CHRM1HTR1A | |
| SCHEMBL13533345 | 0.78 | HTR7 (0.66) | HTR7CHRM3CHRM2CHRM1HTR1A | |
| SCHEMBL13533346 | 0.78 | HTR7 (0.70) | HTR7CHRM3CHRM2CHRM1HTR1A | |
| SCHEMBL13533343 | 0.78 | HTR7 (0.70) | HTR7CHRM3CHRM2CHRM1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4845221-A | ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-07-04 | — | — | US | claimed |
| US-4845221-A | ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-07-04 | — | — | US | disclosed |