SCHEMBL10555286

SCHEMBL10555286

CCCCC(Cl)C(=O)OC(=O)C(Cl)CCCC

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.45
CA1 P00915 4/20 0.45
TSHR P16473 2/20 0.40
CYP3A4 P08684 1/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAPK1 P28482 1/20 0.40
NAAA Q02083 1/20 0.39
ZDHHC7 Q9NXF8 1/20 0.38
ALDH1A1 P00352 2/20 0.38
DPP7 Q9UHL4 1/20 0.37
SLC15A1 P46059 1/20 0.37
FDPS P14324 1/20 0.37
ACHE P22303 1/20 0.36
BACE1 P56817 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29190383 0.93 ZDHHC7 (0.46) CA2CA1NAAAZDHHC7FDPS
SCHEMBL29190362 0.91 ZDHHC7 (0.48) CA2NAAAZDHHC7
SCHEMBL29190404 0.91 ZDHHC7 (0.48) CA2NAAAZDHHC7
SCHEMBL29190389 0.91 ZDHHC7 (0.48) CA2NAAAZDHHC7
SCHEMBL11575927 0.91 ZDHHC7 (0.48) CA2NAAAZDHHC7
SCHEMBL29011446 0.91 ZDHHC7 (0.48) CA2NAAAZDHHC7
SCHEMBL8155883 0.89 CA2 (0.44) CA2CA1TSHRCYP3A4ATM
SCHEMBL27835345 0.87 ALDH1A1 (0.50) CA2CA1TSHRCYP3A4ATM
SCHEMBL10853428 0.86 HDAC7 (0.39) CA2CA1TSHRCYP3A4ATM
SCHEMBL27531946 0.85 NAAA (0.48) CA2CA1TSHRCYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119505178-B Cured product of organic phosphine modified unsaturated resin and polyhalogenated compound and preparation method thereof 浙江工业大学 2025-04-04 CN disclosed
CN-119505178-A Cured product of organic phosphine modified unsaturated resin and polyhalogenated compound and preparation method thereof 浙江工业大学 2025-02-25 CN disclosed
CN-117624613-A Degradable phosphorus/silicon composite antibacterial/flame-retardant material and preparation method thereof 浙江工业大学 2024-03-01 CN disclosed
US-4883876-A CEREBRAL VASCULAR DISORDERS, ARTERIOSCLEROSIS, STROKE, DEMENTIA TAISHO PHARMACEUTICAL CO., LTD. (JP) 1989-11-28 US disclosed
EP-0307167-A2 Vincaminic acid derivatives TAISHO PHARMACEUTICAL CO. LTD (JP) 1989-03-15 EP disclosed
US-4584371-A Catalytic process for preparing 3-ester-methyl cephalosporins from desacetyl-7-aminocephalosporanic acid THE UPJOHN COMPANY (US) 1986-04-22 US disclosed
EP-0153874-A2 Cephalosporin intermediates and their preparation THE UPJOHN COMPANY (US) 1985-09-04 EP disclosed