Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10561285 | 0.90 | P2RX4 (0.39) | MEN1KMT2ANPSR1P2RX4 | |
| SCHEMBL10559033 | 0.88 | ALDH1A1 (0.38) | KMT2A | |
| SCHEMBL10560234 | 0.79 | P2RX4 (0.38) | P2RX4 | |
| SCHEMBL10558916 | 0.75 | GABRA1 (0.37) | — | |
| SCHEMBL10557100 | 0.74 | — | — | |
| SCHEMBL10558192 | 0.74 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL10559314 | 0.70 | HTR2C (0.32) | — | |
| SCHEMBL10560113 | 0.68 | P2RX4 (0.38) | KMT2AP2RX4 | |
| SCHEMBL10555665 | 0.67 | P2RX4 (0.35) | P2RX4 | |
| SCHEMBL10559856 | 0.66 | P2RX4 (0.33) | MEN1KMT2AP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4803269-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4707473-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-11-17 | — | — | US | disclosed |