Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30817696 | 0.84 | ALDH1A1 (0.52) | CES2CES1NPC1RAB9AMAOB | |
| SCHEMBL31302316 | 0.83 | TTR (0.50) | CES2CES1NPC1RAB9AMAOB | |
| SCHEMBL9215548 | 0.83 | NPC1 (0.47) | CES2CES1NPC1RAB9AMAOB | |
| SCHEMBL104151 | 0.83 | TTR (0.50) | CES2CES1NPC1RAB9AMAOB | |
| Bromide SCHEMBL11166294 | 0.81 | TTR (0.48) | CES2CES1NPC1RAB9AMAOB | |
| SCHEMBL31537525 | 0.81 | PARP1 (0.48) | CES2CES1NPC1RAB9AMAOB | |
| SCHEMBL145505 | 0.81 | PARP1 (0.48) | CES2CES1NPC1RAB9AMAOB | |
| Fluoride SCHEMBL11181401 | 0.81 | TTR (0.48) | CES2CES1NPC1RAB9AMAOB | |
| SCHEMBL146573 | 0.81 | NPC1 (0.46) | CES2CES1NPC1RAB9AMAOB | |
| SCHEMBL381027 | 0.81 | NPC1 (0.44) | CES2CES1NPC1RAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059365-A2 | 3-Bromo-4-fluoro-benzyl derivatives, and methods for their preparation | BAYER AG (DE) | 1982-09-08 | — | — | EP | claimed |
| EP-0024516-B1 | 4-FLUORO-3-BROMOBENZOYL FLUORIDE, PROCESS FOR ITS PREPARATION AND FOR THE PREPARATION OF 4-FLUORO-3-BROMOBENZOIC ACID THEREFROM | BAYER AG (DE) | 1982-07-28 | — | — | EP | claimed |
| US-4326087-A | REACTING 3-BROMO-4-FLUORO-BENZYL ALCOHOL WITH A CHLORINATING OR BROMINATING AGENT OR 3-BROMO-4-FLUORO-BENZOYL FLUORIDE WITH A HYDRIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-20 | — | — | US | claimed |
| EP-0024612-A2 | New 4-fluoro-3-phenoxy-benzyl-ethers, process for their preparation and their use | BAYER AG (DE) | 1981-03-11 | — | — | EP | claimed |
| EP-0024516-A1 | 4-Fluoro-3-bromobenzoyl fluoride, process for its preparation and for the preparation of 4-fluoro-3-bromobenzoic acid therefrom | BAYER AG (DE) | 1981-03-11 | — | — | EP | claimed |
| CN-118439937-A | Synthetic method of 4-fluoro-3-phenoxybenzaldehyde serving as key intermediate of insect repellent | 康龙化成(绍兴)药业有限公司 | 2024-08-06 | — | — | CN | disclosed |
| US-4845249-A | 4-fluoro-3-bromo benzaldehyde acetals | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
| EP-0293747-A2 | Process for the preparation of fluoride-substituted carboxylic-acid chlorides | BASF Aktiengesellschaft (DE) | 1988-12-07 | — | — | EP | disclosed |
| US-4748257-A | 4-fluoro-3-phenoxy-benzaldehyde acetals | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |
| US-4626601-A | Preparation of 4-fluoro-3-phenoxy-benzal-dehyde acetals and intermediates therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-02 | — | — | US | disclosed |
| EP-0048411-B1 | PROCESS FOR PREPARING 3-BROMO-4-FLUORO-BENZALDEHYDE ACETALS, INTERMEDIATES AND THEIR PREPARATION | BAYER AG (DE) | 1986-11-12 | — | — | EP | disclosed |
| US-4555370-A | CYANTATION OF ACYL. FLUORIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-26 | — | — | US | disclosed |
| EP-0044002-A1 | Process for preparing 3-bromo-4-fluorobenzaldehyde (-acetals),3-bromo- 4-fluoro-benzoic acid nitrile and its preparation | BAYER AG (DE) | 1982-01-20 | — | — | EP | disclosed |
| EP-0038987-A1 | Process for preparing acyl cyanides | BAYER AG (DE) | 1981-11-04 | — | — | EP | disclosed |
| EP-0024612-A2 | New 4-fluoro-3-phenoxy-benzyl-ethers, process for their preparation and their use | BAYER AG (DE) | 1981-03-11 | — | — | EP | disclosed |
| EP-0024516-A1 | 4-Fluoro-3-bromobenzoyl fluoride, process for its preparation and for the preparation of 4-fluoro-3-bromobenzoic acid therefrom | BAYER AG (DE) | 1981-03-11 | — | — | EP | disclosed |
| EP-0024516-A1 | 4-Fluoro-3-bromobenzoyl fluoride, process for its preparation and for the preparation of 4-fluoro-3-bromobenzoic acid therefrom | BAYER AG (DE) | 1981-03-11 | — | — | EP | disclosed |
| EP-0024516-A1 | 4-Fluoro-3-bromobenzoyl fluoride, process for its preparation and for the preparation of 4-fluoro-3-bromobenzoic acid therefrom | BAYER AG (DE) | 1981-03-11 | — | — | EP | disclosed |
| EP-0024624-A2 | 4-Fluoro-3-phenoxy-benzaldehyde acetals, process for their preparation and intermediate products therefor | BAYER AG (DE) | 1981-03-11 | — | — | EP | disclosed |
| EP-0017882-A1 | Process for the preparation of 3-phenoxy-4-fluoro-benzoic acid | BAYER AG (DE) | 1980-10-29 | — | — | EP | disclosed |