Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31302316 | 1.00 | TTR (0.50) | TTRLMNARAB9AHTTMAPK1 | |
| Hydrochloric Acid SCHEMBL6520005 | 0.98 | TTR (0.48) | TTRLMNARAB9AHTTMAPK1 | |
| Bromide SCHEMBL11166294 | 0.98 | TTR (0.48) | TTRLMNARAB9AHTTMAPK1 | |
| Fluoride SCHEMBL11181401 | 0.98 | TTR (0.48) | TTRLMNARAB9AHTTMAPK1 | |
| Trichloroacetic Acid SCHEMBL7814387 | 0.89 | TTR (0.41) | TTRLMNARAB9AHTTMAPK1 | |
| SCHEMBL30817696 | 0.84 | ALDH1A1 (0.52) | RAB9APGRTSHRCA1CA2 | |
| SCHEMBL10884738 | 0.83 | CES2 (0.52) | TTRRAB9APGRCES2CES1 | |
| SCHEMBL10555693 | 0.83 | CES2 (0.45) | RAB9APGRCA1CA2CES2 | |
| SCHEMBL286942 | 0.83 | HTT (0.53) | TTRLMNARAB9AHTTMAPK1 | |
| SCHEMBL9215548 | 0.83 | NPC1 (0.47) | RAB9APGRCA1CA2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 713 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| CN-114057724-B | BTK inhibitor | 鲁南制药集团股份有限公司 | 2025-01-03 | — | — | CN | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| CN-114057724-A | BTK inhibitor | 鲁南制药集团股份有限公司 | 2022-02-18 | — | — | CN | claimed |
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-11 | — | — | US | claimed |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | Indiana University Research and Technology Corpora tion (US) | 2016-06-23 | — | — | US | claimed |
| US-9217012-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-12-22 | — | — | US | claimed |
| CN-103183647-A | Novel preparation method of 3-{[2-[3-oxygen-(1,2-benzisothiazole-6-yl)methoxyl-5-(2-hydroxy-4-cyclopentyloxyl)]phenyl}propionic acid | TIANJIN INT JOINT ACADEMY BIOTECHNOLOGY & MEDICINE | 2013-07-03 | — | — | CN | claimed |
| US-20120088720-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) | 2012-04-12 | — | — | US | claimed |
| WO-2010118241-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2010-10-14 | — | — | WO | claimed |
| US-6946025-B2 | Process for preparing tetra-amide compounds | XEROX CORPORATION (US) | 2005-09-20 | — | — | US | claimed |
| US-20050090690-A1 | Process for preparing tetra-amide compounds | XEROX CORPORATION | 2005-04-28 | — | — | US | claimed |
| EP-0048375-B1 | PROCESS FOR THE PREPARATION OF 3-BROMO-4-FLUORO-BENZOIC ACID | BAYER AG (DE) | 1983-09-07 | — | — | EP | claimed |
| US-4393232-A | Preparation of 3-bromo-4-fluoro-benzoic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | claimed |
| US-4386035-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-05-31 | — | — | US | claimed |
| EP-0024516-B1 | 4-FLUORO-3-BROMOBENZOYL FLUORIDE, PROCESS FOR ITS PREPARATION AND FOR THE PREPARATION OF 4-FLUORO-3-BROMOBENZOIC ACID THEREFROM | BAYER AG (DE) | 1982-07-28 | — | — | EP | claimed |
| EP-0048914-A1 | Process for the preparation of 3-bromo-4-fluorobenzyl alcohol, intermediate products therefor, and process for the preparation of these intermediate products | BAYER AG (DE) | 1982-04-07 | — | — | EP | claimed |
| EP-0048375-A1 | Process for the preparation of 3-bromo-4-fluoro-benzoic acid | BAYER AG (DE) | 1982-03-31 | — | — | EP | claimed |
| EP-0024516-A1 | 4-Fluoro-3-bromobenzoyl fluoride, process for its preparation and for the preparation of 4-fluoro-3-bromobenzoic acid therefrom | BAYER AG (DE) | 1981-03-11 | — | — | EP | claimed |
| EP-0017882-A1 | Process for the preparation of 3-phenoxy-4-fluoro-benzoic acid | BAYER AG (DE) | 1980-10-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | PTPRCAP, PTPRF, PTPRS | TTR 347/4885LMNA 4734/4885RAB9A 2114/4885 |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | TTR 347/4885LMNA 4734/4885RAB9A 2114/4885 |
| US-20050090690-A1 | Process for preparing tetra-amide compounds | TAF9, TAF5, TAF1 | TTR 22/4885LMNA 2024/4885RAB9A 789/4885 |
| US-20120088720-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | TTR 347/4885LMNA 4734/4885RAB9A 2114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.