SCHEMBL9215548

SCHEMBL9215548

O=C(Br)c1ccc(F)c(Br)c1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
MAOB P27338 3/20 0.42
CTSL P07711 1/20 0.41
IDO1 P14902 2/20 0.41
TDO2 P48775 1/20 0.41
PGR P06401 1/20 0.40
MAOA P21397 2/20 0.39
HDAC1 Q13547 3/20 0.38
HDAC6 Q9UBN7 3/20 0.38
HDAC8 Q9BY41 1/20 0.38
ALDH1A1 P00352 1/20 0.37
VCP P55072 1/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
SLC9A1 P19634 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30817696 0.84 ALDH1A1 (0.52) NPC1RAB9ACES2CES1MAOB
SCHEMBL31302316 0.83 TTR (0.50) NPC1RAB9ACES2CES1MAOB
SCHEMBL10555693 0.83 CES2 (0.45) NPC1RAB9ACES2CES1MAOB
SCHEMBL104151 0.83 TTR (0.50) NPC1RAB9ACES2CES1MAOB
SCHEMBL146573 0.81 NPC1 (0.46) NPC1RAB9ACES2CES1MAOB
SCHEMBL31537525 0.81 PARP1 (0.48) NPC1RAB9ACES2CES1MAOB
SCHEMBL381027 0.81 NPC1 (0.44) NPC1RAB9ACES2CES1MAOB
Hydrochloric Acid SCHEMBL6520005 0.81 TTR (0.48) NPC1RAB9ACES2CES1MAOB
Fluoride SCHEMBL11181401 0.81 TTR (0.48) NPC1RAB9ACES2CES1MAOB
Bromide SCHEMBL11166294 0.81 TTR (0.48) NPC1RAB9ACES2CES1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120158100-A Preparation method of high-temperature-resistant corrosion-resistant alloy rubber 上海焦能新材料有限公司 2025-06-17 CN claimed
CN-117986663-A High-temperature-resistant corrosion-resistant alloy rubber and preparation method thereof 上海焦能新材料有限公司 2024-05-07 CN claimed
CN-115399179-A Application of polysaccharide-based cationic polymer in prevention and treatment of soil-borne diseases of agriculture and forestry 中国科学院化学研究所 2022-11-29 CN claimed
CN-120158100-A Preparation method of high-temperature-resistant corrosion-resistant alloy rubber 上海焦能新材料有限公司 2025-06-17 CN disclosed
CN-115399179-B Application of polysaccharide-based cationic polymer in preventing and controlling soil-borne diseases of agriculture and forestry 中国科学院化学研究所 2024-10-29 CN disclosed
CN-117986663-A High-temperature-resistant corrosion-resistant alloy rubber and preparation method thereof 上海焦能新材料有限公司 2024-05-07 CN disclosed
CN-115399179-A Application of polysaccharide-based cationic polymer in prevention and treatment of soil-borne diseases of agriculture and forestry 中国科学院化学研究所 2022-11-29 CN disclosed
EP-0549601-B1 METHOD OF PREPARING EXTENSIVELY FLUORINATED ALKYL BROMIDES RIEDEL DE HAEN AG (DE) 1995-04-26 EP disclosed
US-5336818-A Reacting substantially fluorinated alkyl iodides with organic bromine compounds RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1994-08-09 US disclosed
WO-1992004307-A1 METHOD OF PREPARING EXTENSIVELY FLUORINATED ALKYL BROMIDES RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1992-03-19 WO disclosed
US-4845249-A 4-fluoro-3-bromo benzaldehyde acetals BAYER AKTIENGESELLSCHAFT (DE) 1989-07-04 US disclosed
EP-0061004-A1 3-Bromo-4-fluorobenzaldehyde and its acetals, and process for their preparation BAYER AG (DE) 1982-09-29 EP disclosed
EP-0059365-A2 3-Bromo-4-fluoro-benzyl derivatives, and methods for their preparation BAYER AG (DE) 1982-09-08 EP disclosed
US-4348538-A IMINES, GLYOCYLIC ACIDS, BENZOYL CYANIDES BAYER AKTIENGESELLSCHAFT (DE) 1982-09-07 US disclosed
EP-0048411-A2 Process for preparing 3-bromo-4-fluoro-benzaldehyde acetals, intermediates and their preparation BAYER AG (DE) 1982-03-31 EP disclosed
EP-0044002-A1 Process for preparing 3-bromo-4-fluorobenzaldehyde (-acetals),3-bromo- 4-fluoro-benzoic acid nitrile and its preparation BAYER AG (DE) 1982-01-20 EP disclosed
EP-0034741-A2 Process for the preparation of a substituted bromofluorobenzene and 3-bromo-4-fluorobenzonitrile RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1981-09-02 EP disclosed
EP-0024612-A2 New 4-fluoro-3-phenoxy-benzyl-ethers, process for their preparation and their use BAYER AG (DE) 1981-03-11 EP disclosed
EP-0024624-A2 4-Fluoro-3-phenoxy-benzaldehyde acetals, process for their preparation and intermediate products therefor BAYER AG (DE) 1981-03-11 EP disclosed
EP-0017882-A1 Process for the preparation of 3-phenoxy-4-fluoro-benzoic acid BAYER AG (DE) 1980-10-29 EP disclosed