Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL653579 | 0.81 | ALDH1A1 (1.00) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL8675809 | 0.78 | CA12 (0.49) | ALDH1A1MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL26785501 | 0.78 | MAOA (0.45) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL29853348 | 0.78 | MAOA (0.45) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL10867494 | 0.78 | ALDH1A1 (0.76) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL3809960 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL29853608 | 0.76 | PREP (0.42) | MAPTKMT2A | |
| SCHEMBL8798399 | 0.76 | ALDH1A1 (0.62) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL26781090 | 0.76 | PREP (0.42) | MAPTKMT2A | |
| SCHEMBL10925574 | 0.75 | MAPT (0.85) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4889858-A | ANTIHYPOXIC AGENTS, ANTICONVULSANTS, LIPID PEROXIDATION INHIBITORS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-12-26 | — | — | US | disclosed |
| EP-0269755-A1 | DIBENZ b,e OXEPIN DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME AS ACTIVE INGREDIENT | Dainippon Pharmaceutical Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |