Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27721078 | 1.00 | AOC3 (0.55) | AOC3TSHRL3MBTL1PDE4APDE4B | |
| SCHEMBL11241604 | 0.94 | AOC3 (0.50) | AOC3TSHRL3MBTL1PDE4APDE4B | |
| SCHEMBL8125387 | 0.83 | TSHR (0.48) | AOC3TSHRL3MBTL1KMT2ANPC1 | |
| SCHEMBL2155273 | 0.82 | AOC3 (0.51) | AOC3TSHRL3MBTL1CES2CES1 | |
| SCHEMBL7442599 | 0.82 | L3MBTL1 (0.54) | AOC3TSHRL3MBTL1CES2CES1 | |
| SCHEMBL17466002 | 0.81 | ALDH1A1 (0.48) | AOC3L3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL15617614 | 0.81 | AOC3 (0.48) | AOC3L3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL11854342 | 0.81 | ALDH1A1 (0.46) | AOC3TSHRPDE4APDE4BPDE4C | |
| SCHEMBL192456 | 0.81 | TSHR (0.60) | TSHRKMT2ANPC1 | |
| SCHEMBL30045078 | 0.81 | TSHR (0.60) | TSHRKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102007095-B | Method for producing optically active cyanohydrin compound | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2014-10-08 | — | — | CN | disclosed |
| US-8309753-B2 | Method for producing optically active cyanohydrin compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-11-13 | — | — | US | disclosed |
| US-7985572-B2 | Modified nitrilases and their use in methods for the production of carboxylic acids | BASF SE (DE) | 2011-07-26 | — | — | US | disclosed |
| CN-102007095-A | Method for producing optically active cyanohydrin compound | SUMITOMO CHEMICAL CO | 2011-04-06 | — | — | CN | disclosed |
| US-20110034718-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYANOHYDRIN COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-02-10 | — | — | US | disclosed |
| US-7872014-B2 | Anaplastic lymphoma kinase modulators and methods of use | EXELIXIS, INC. (US) | 2011-01-18 | — | — | US | disclosed |
| EP-2264005-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYANOHYDRIN COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2010-12-22 | — | — | EP | disclosed |
| EP-1599584-B1 | MODIFIED NITRILASES AND THEIR USE IN METHODS FOR THE PRODUCTION OF CARBOXYLIC ACIDS | BASF SE (DE) | 2009-07-01 | — | — | EP | disclosed |
| EP-1648455-A4 | ANAPLASTIC LYMPHOMA KINASE MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2009-03-04 | — | — | EP | disclosed |
| CN-101238092-A | Process for production of 2-hydroxy esters | NIPPOH CHEMICALS (JP) | 2008-08-06 | — | — | CN | disclosed |
| WO-2004076655-A1 | MODIFIED NITRILASES AND THEIR USE IN METHODS FOR THE PRODUCTION OF CARBOXYLIC ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-10 | — | — | WO | disclosed |
| EP-0561637-B1 | A catalyst for asymmetric induction | SUMITOMO CHEMICAL CO (JP) | 1997-02-26 | — | — | EP | disclosed |
| EP-0505089-B1 | A catalyst for asymmetric induction | SUMITOMO CHEMICAL CO (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5308820-A | Catalyst for asymmetric induction | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-05-03 | — | — | US | disclosed |
| US-5288682-A | Catalyst for asymmetric induction | SUMITOMO CHEMICAL CO., LTD. (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0561637-A2 | A catalyst for asymmetric induction | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0505089-A1 | A catalyst for asymmetric induction | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-09-23 | — | — | EP | disclosed |
| EP-0276375-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE ALPHA-HYDROXYNITRILES | Degussa Aktiengesellschaft (DE) | 1992-05-06 | — | — | EP | disclosed |
| EP-0276375-A2 | Process for the preparation of optically active alpha-hydroxynitriles | Degussa Aktiengesellschaft (DE) | 1988-08-03 | — | — | EP | disclosed |
| US-3937719-A | (4-OXO-4H-1-BENZOPYRAN-2-YL)-OXAMIC ACID, SALTS AND ESTERS ANTI-ALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034718-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE CYANOHYDRIN COMPOUND | CBR3, ACSL3, CCNL2 | AOC3 674/4885TSHR 4501/4885L3MBTL1 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.