Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562450 | 0.82 | MAOB (0.50) | MAOBMAPTIDO1PGRBRD4 | |
| SCHEMBL10561382 | 0.73 | MAOB (0.46) | MAOBKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11816671 | 0.72 | ALDH1A1 (0.50) | KDM4EALDH1A1ALOX15SMN1; SMN2HSD17B10 | |
| SCHEMBL9774494 | 0.69 | SLC6A2 (0.43) | KDM4EMEN1KMT2AMAPTPOLB | |
| SCHEMBL28975294 | 0.67 | PGR (0.56) | MAPTPOLBIDO1PGRBRD4 | |
| SCHEMBL17807750 | 0.67 | MAOB (0.47) | MAOBKDM4ESMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL10920990 | 0.67 | BRD4 (0.40) | MAOBMAPTIDO1BRD4 | |
| SCHEMBL12520453 | 0.66 | IDO1 (0.44) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23836089 | 0.65 | IDO1 (0.46) | MAOBKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7310972 | 0.65 | IDO1 (0.46) | MAOBKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826847-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-05-02 | — | — | US | disclosed |
| EP-0170117-A1 | Oxindole derivatives, process for their preparation, pharmaceutical compositions containing them and intermediate compounds | Roche Diagnostics GmbH (DE) | 1986-02-05 | — | — | EP | disclosed |