SCHEMBL10558677

SCHEMBL10558677

c1ccc(CCON=C2CC(=NOCCc3ccccc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
IDO1 P14902 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
FFAR1 O14842 1/20 0.35
FURIN P09958 1/20 0.33
KEAP1 Q14145 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
CASP1 P29466 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10555448 0.77 HTR3E (0.43) TAAR1TDP1RAB9AFURINALDH1A1
Hydrochloric Acid SCHEMBL10557245 0.75 FURIN (0.36) RAB9AFURIN
SCHEMBL10561667 0.74 USP8 (0.43) FURINALDH1A1HPGD
SCHEMBL10556400 0.72 MAPK8 (0.52) FURINALDH1A1HPGDALOX15
SCHEMBL10557856 0.72 SCN1A (0.40) ALDH1A1
SCHEMBL6873643 0.69 CA1 (0.45) TAAR1TDP1CA1CA2CA9
SCHEMBL10555801 0.67 CASP6 (0.47) TDP1IDO1NPC1RAB9AFURIN
SCHEMBL6873640 0.67 CA1 (0.44) TAAR1TDP1CA1CA2CA9
SCHEMBL3819917 0.67 CA1 (0.48) TAAR1TDP1CA1CA2CA9
SCHEMBL4883430 0.66 TAAR1 (0.54) TAAR1TDP1CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4804684-A ANTICONVULSANTS, ANALGESICS PANMEDICA S.A. (FR) 1989-02-14 US disclosed