Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10371785 | 0.88 | MAPT (0.39) | PKMMAPK1KMT2AMEN1POLB | |
| SCHEMBL10565318 | 0.82 | PKM (0.43) | PKMMAPK1KMT2AMEN1POLB | |
| SCHEMBL10565314 | 0.81 | PKM (0.42) | PKMMAPK1KMT2AMEN1POLB | |
| SCHEMBL10522944 | 0.78 | GABRB3 (0.41) | PKMKMT2AMEN1ALDH1A1THRB | |
| SCHEMBL10388695 | 0.78 | MAPT (0.37) | PKMMAPK1KMT2AMEN1POLB | |
| SCHEMBL10562897 | 0.76 | GAA (0.50) | PKMMAPK1PTGS1PTGS2KMT2A | |
| SCHEMBL1535809 | 0.76 | PKM (0.39) | PKMKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL9526617 | 0.75 | PKM (0.47) | PKMMAPK1KMT2AMEN1POLB | |
| SCHEMBL10687409 | 0.75 | PKM (0.47) | PKMKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL10373706 | 0.75 | MAPT (0.46) | PKMMAPK1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814001-A | PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-03-21 | — | — | US | disclosed |
| US-4772310-A | 5-acylamino-pyrazole derivatives, composition containing them, and their use as herbicides and plant growth | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-20 | — | — | US | disclosed |
| EP-0248315-A2 | 5-Acylamino pyrazole derivatives | BAYER AG (DE) | 1987-12-09 | — | — | EP | disclosed |