Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526634 | 0.84 | PKM (0.49) | PKMMAPK1TSHRALDH1A1CDK4 | |
| SCHEMBL10769910 | 0.84 | PKM (0.44) | PKMMAPK1TSHRALDH1A1CDK4 | |
| SCHEMBL10609185 | 0.82 | PKM (0.47) | PKMMAPK1TSHRALDH1A1CDK4 | |
| SCHEMBL10623535 | 0.78 | PKM (0.47) | PKMMAPK1TSHRALDH1A1CDK4 | |
| SCHEMBL10559340 | 0.75 | PKM (0.47) | PKMMAPK1ALDH1A1MAPTMEN1 | |
| SCHEMBL9525455 | 0.74 | TDP1 (0.47) | PKMALDH1A1GPR35MAPTMEN1 | |
| SCHEMBL10623013 | 0.70 | MAPK1 (0.40) | PKMMAPK1ALDH1A1CDK4CCND1 | |
| SCHEMBL10652406 | 0.70 | TSHR (0.41) | PKMMAPK1TSHRALDH1A1GPR35 | |
| SCHEMBL9526043 | 0.70 | TDP1 (0.50) | PKMMAPK1TSHRALDH1A1CYP3A4 | |
| SCHEMBL8522013 | 0.69 | GLS (0.50) | PKMMAPK1TSHRALDH1A1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257296-B1 | 4-CYANO(NITRO)-5-OXY(THIO)-PYRAZOLE DERIVATIVES | BAYER AG (DE) | 1993-05-12 | — | — | EP | disclosed |
| US-4770692-A | 4-cyano(nitro)-5-oxy(thio)-pyrazole derivatives, composition containing them, and herbicidal and plant growth regulating methods of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | disclosed |