Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.37 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.37 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10560775 | 0.90 | STAT3 (0.46) | STAT3KMT2ATSHRMAPK1ADRB2 | |
| SCHEMBL10563639 | 0.85 | STAT3 (0.50) | STAT3KMT2ATSHRMAPK1ADRB2 | |
| SCHEMBL10560764 | 0.84 | STAT3 (0.46) | STAT3KMT2ATSHRMAPK1ADRB2 | |
| SCHEMBL583970 | 0.82 | ADRB2 (0.54) | STAT3ADRB2TDP1 | |
| SCHEMBL10562164 | 0.74 | STAT3 (0.58) | STAT3TSHRMAPK1TDP1 | |
| SCHEMBL9426477 | 0.73 | STAT3 (0.59) | STAT3KMT2ATSHRADRB2TDP1 | |
| SCHEMBL10669008 | 0.73 | STAT3 (0.54) | STAT3KMT2ATSHRADRB2TDP1 | |
| SCHEMBL9534547 | 0.73 | STAT3 (0.46) | STAT3HSP90AA1 | |
| SCHEMBL9870208 | 0.72 | STAT3 (0.64) | STAT3KMT2AADRB2TDP1HTT | |
| Hydrochloric Acid SCHEMBL9427147 | 0.72 | STAT3 (0.58) | STAT3KMT2ATSHRADRB2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4864023-A | MICROBIOCIDES, BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4801584-A | ANTIMICROBIAL | HOFFMANN-LA ROCHE INC. (US) | 1989-01-31 | — | — | US | disclosed |