Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.53 |
| ▸ | DRD3 | P35462 | 3/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10564984 | 0.97 | DRD2 (0.52) | DRD2DRD3ADRA2BADRA2CHTR2B | |
| SCHEMBL10559935 | 0.97 | DRD2 (0.52) | DRD2DRD3ADRA2BADRA2CHTR2B | |
| SCHEMBL10563605 | 0.96 | DRD2 (0.51) | DRD2DRD3ADRA2BADRA2CHTR2B | |
| SCHEMBL21055572 | 0.92 | DRD2 (0.53) | DRD2DRD3ADRA2BADRA2CHTR2B | |
| SCHEMBL3314494 | 0.92 | DRD2 (0.53) | DRD2DRD3ADRA2BADRA2CHTR2B | |
| SCHEMBL21054909 | 0.92 | DRD2 (0.53) | DRD2DRD3ADRA2BADRA2CHTR2B | |
| SCHEMBL10561934 | 0.91 | DRD2 (0.49) | DRD2DRD3ADRA2BADRA2CHTR2B | |
| SCHEMBL10561655 | 0.90 | DRD2 (0.42) | DRD2DRD3ADRA2BADRA2CHTR2B | |
| SCHEMBL7380370 | 0.88 | DRD2 (0.55) | DRD2DRD3ADRA2BADRA2CHTR2B | |
| SCHEMBL7372752 | 0.86 | LMNA (0.47) | DRD2DRD3ADRA2BADRA2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4816471-A | NERVOUS SYSTEM DISORDERS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILLE-DE FRANCE (FR) | 1989-03-28 | — | — | US | claimed |