SCHEMBL3314494

SCHEMBL3314494

CCC(NC(=O)c1cc(S(=O)(=O)CC)c(N)cc1OC)C1CCCN1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 3/20 0.53
ADRA2B P18089 2/20 0.53
ADRA2C P18825 2/20 0.53
DRD3 P35462 2/20 0.53
HTR2B P41595 2/20 0.53
KCNH2 Q12809 2/20 0.53
HRH3 Q9Y5N1 2/20 0.53
LMNA P02545 1/20 0.53
ADRA2A P08913 1/20 0.53
ALOX15 P16050 1/20 0.53
TSHR P16473 1/20 0.53
HTR2A P28223 1/20 0.53
MAPK1 P28482 1/20 0.53
HTR7 P34969 1/20 0.53
HRH1 P35367 1/20 0.53
HTR4 Q13639 7/20 0.39
SLC6A4 P31645 1/20 0.36
HTR3A P46098 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21055572 1.00 DRD2 (0.53) DRD2ADRA2BADRA2CDRD3HTR2B
SCHEMBL21054909 1.00 DRD2 (0.53) DRD2ADRA2BADRA2CDRD3HTR2B
SCHEMBL7372752 0.94 LMNA (0.47) DRD2ADRA2BADRA2CDRD3HTR2B
SCHEMBL7381604 0.93 DRD2 (0.44) DRD2ADRA2BADRA2CDRD3HTR2B
SCHEMBL10559503 0.92 DRD2 (0.53) DRD2ADRA2BADRA2CDRD3HTR2B
SCHEMBL10559935 0.91 DRD2 (0.52) DRD2ADRA2BADRA2CDRD3HTR2B
SCHEMBL10564984 0.91 DRD2 (0.52) DRD2ADRA2BADRA2CDRD3HTR2B
SCHEMBL7380370 0.90 DRD2 (0.55) DRD2ADRA2BADRA2CDRD3HTR2B
SCHEMBL10561934 0.90 DRD2 (0.49) DRD2ADRA2BADRA2CDRD3HTR2B
SCHEMBL10563605 0.90 DRD2 (0.51) DRD2ADRA2BADRA2CDRD3HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112236138-B Crystal forms and methods of making the same 赛诺维信制药公司 2024-05-31 CN disclosed
EP-3720435-B1 CRYSTAL FORMS AND PRODUCTION METHODS THEREOF SUNOVION PHARMACEUTICALS INC (US) 2024-03-06 EP disclosed
US-11767293-B2 Crystal forms and production methods thereof SUNOVION PHARMACEUTICALS INC. (US) 2023-09-26 US disclosed
US-20230072389-A1 CRYSTAL FORMS AND PRODUCTION METHODS THEREOF SUNOVION PHARMACEUTICALS INC. (US) 2023-03-09 US disclosed
US-11370753-B2 Crystal forms and production methods thereof SUNOVION PHARMACEUTICALS INC. (US) 2022-06-28 US disclosed
US-20210061759-A1 CRYSTAL FORMS AND PRODUCTION METHODS THEREOF SUNOVION PHARMACEUTICALS INC. (US) 2021-03-04 US disclosed
CN-112236138-A Crystalline forms and methods of making the same 赛诺维信制药公司 2021-01-15 CN disclosed
EP-3720435-A1 CRYSTAL FORMS AND PRODUCTION METHODS THEREOF Sunovion Pharmaceuticals Inc. (US) 2020-10-14 EP disclosed
US-10800738-B2 Crystal forms and production methods thereof SUNOVION PHARMACEUTICALS INC. (US) 2020-10-13 US disclosed
US-20200165200-A1 CRYSTAL FORMS AND PRODUCTION METHODS THEREOF SUNOVION PHARMACEUTICALS INC. (US) 2020-05-28 US disclosed
US-20190315686-A1 CRYSTAL FORMS AND PRODUCTION METHODS THEREOF SUNOVION PHARMACEUTICALS INC. 2019-10-17 US disclosed
US-10377708-B2 Crystal forms and production methods thereof SUNOVION PHARMACEUTICALS INC. (US) 2019-08-13 US disclosed
WO-2019113084-A1 CRYSTAL FORMS AND PRODUCTION METHODS THEREOF SUNOVION PHARMACEUTICALS INC. (US) 2019-06-13 WO disclosed
US-20190169123-A1 CRYSTAL FORMS AND PRODUCTION METHODS THEREOF SUNOVION PHARMACEUTICALS INC. 2019-06-06 US disclosed
US-20100105755-A1 SUBSTITUTED BENZAMIDE MODULATORS OF DOPAMINE RECEPTOR AUSPEX PHARMACEUTICALS, INC. (US) 2010-04-29 US disclosed
US-6187807-B1 ADMINISTERING (S)(-)-AMISULPRIDE OR SALT THEREOF FREE OF THE (R)-(+)-STEREOISOMER, TO ELICIT ANTIPSYCHOTIC PROPERTIES IN A PATIENT SANOFI-SYNTHELABO (FR) 2001-02-13 US disclosed
US-6169094-B1 ANTIPSYCHOTIC AGENTS SANOFI-SYNTHELABO (FR) 2001-01-02 US disclosed
EP-0177654-A1 Synergistic contraceptive mixture SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) 1986-04-16 EP disclosed
US-4401822-A ANISEROTONINE AGENTS; APOMORPHINE ANTAGONIST SOCIETE DE'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE FRANCE (FR) 1983-08-30 US disclosed
US-4294828-A ANTIEMETIC AND ANTISEROTONIN SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE DE-FRANCE (FR) 1981-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10800738-B2 Crystal forms and production methods thereof CYP4F3, HMGCR, LSS DRD2 752/4885ADRA2B 474/4885ADRA2C 212/4885
US-11767293-B2 Crystal forms and production methods thereof CYP4F3, HMGCR, LSS DRD2 752/4885ADRA2B 474/4885ADRA2C 212/4885
US-20230072389-A1 CRYSTAL FORMS AND PRODUCTION METHODS THEREOF CYP4F3, HMGCR, LSS DRD2 752/4885ADRA2B 474/4885ADRA2C 212/4885
US-20200165200-A1 CRYSTAL FORMS AND PRODUCTION METHODS THEREOF CYP4F3, HMGCR, LSS DRD2 752/4885ADRA2B 474/4885ADRA2C 212/4885
US-20210061759-A1 CRYSTAL FORMS AND PRODUCTION METHODS THEREOF CYP4F3, HMGCR, LSS DRD2 752/4885ADRA2B 474/4885ADRA2C 212/4885
US-20190169123-A1 CRYSTAL FORMS AND PRODUCTION METHODS THEREOF CYP4F3, HMGCR, LSS DRD2 752/4885ADRA2B 474/4885ADRA2C 212/4885
US-20190315686-A1 CRYSTAL FORMS AND PRODUCTION METHODS THEREOF CYP4F3, HMGCR, LSS DRD2 752/4885ADRA2B 474/4885ADRA2C 212/4885
US-20100105755-A1 SUBSTITUTED BENZAMIDE MODULATORS OF DOPAMINE RECEPTOR DBH, SLC6A3, HTR5A DRD2 44/4885ADRA2B 22/4885ADRA2C 17/4885
US-11370753-B2 Crystal forms and production methods thereof CYP4F3, HMGCR, LSS DRD2 752/4885ADRA2B 474/4885ADRA2C 212/4885
US-10377708-B2 Crystal forms and production methods thereof CYP4F3, HMGCR, LSS DRD2 752/4885ADRA2B 474/4885ADRA2C 212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.