Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 6/20 | 1.00 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.73 |
| ▸ | XDH | P47989 | 1/20 | 0.63 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10560725 | 0.84 | ALOX15 (1.00) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL10564854 | 0.84 | ALOX15 (0.73) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL10561728 | 0.83 | ALOX15 (1.00) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL10562974 | 0.83 | ALOX15 (1.00) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL10562125 | 0.82 | ALOX15 (0.71) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL29482685 | 0.82 | XDH (0.76) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL17938839 | 0.82 | XDH (0.76) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL10564082 | 0.81 | ALOX15 (1.00) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL28705298 | 0.80 | ALOX15 (0.73) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL2072028 | 0.79 | ALOX15 (0.65) | ALOX15ALOX12PIK3CAXDHPFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814346-A | Benzopyrans and use thereof in treating vascular diseases | ZYMA SA (CH) | 1989-03-21 | — | — | US | disclosed |
| EP-0267155-A2 | Bicyclic compounds | Zyma SA (CH) | 1988-05-11 | — | — | EP | disclosed |