Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.71 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.70 |
| ▸ | XDH | P47989 | 1/20 | 0.60 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562974 | 0.84 | ALOX15 (1.00) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL10561640 | 0.82 | ALOX15 (1.00) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL10560725 | 0.82 | ALOX15 (1.00) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL10564854 | 0.82 | ALOX15 (0.73) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL29482685 | 0.80 | XDH (0.76) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL17938839 | 0.80 | XDH (0.76) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL10564082 | 0.79 | ALOX15 (1.00) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL28705298 | 0.78 | ALOX15 (0.73) | ALOX15ALOX12PIK3CAXDHPFKFB3 | |
| SCHEMBL10563531 | 0.78 | MAPT (0.48) | ALOX15ALOX12PIK3CAKDM4EALDH1A1 | |
| SCHEMBL30533224 | 0.76 | XDH (1.00) | ALOX15ALOX12PIK3CAXDHPFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814346-A | Benzopyrans and use thereof in treating vascular diseases | ZYMA SA (CH) | 1989-03-21 | — | — | US | disclosed |
| EP-0267155-A2 | Bicyclic compounds | Zyma SA (CH) | 1988-05-11 | — | — | EP | disclosed |