Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562818 | 0.81 | KDM4E (0.58) | SMN1; SMN2PIM1KDM4EHTTNPC1 | |
| SCHEMBL10561666 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AMEN1HPGDNPSR1 | |
| SCHEMBL28866367 | 0.78 | MAPK1 (0.55) | SMN1; SMN2KMT2AMEN1HPGDNPSR1 | |
| SCHEMBL10562046 | 0.75 | IDO1 (0.41) | SMN1; SMN2KMT2AMEN1HPGDNPSR1 | |
| SCHEMBL10562796 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2AMEN1HPGDNPSR1 | |
| SCHEMBL9229241 | 0.72 | SMN1; SMN2 (0.64) | SMN1; SMN2KMT2AMEN1HPGDNPSR1 | |
| SCHEMBL11454047 | 0.70 | GAA (0.51) | SMN1; SMN2KMT2ANPSR1PIM1KDM4E | |
| SCHEMBL5024019 | 0.68 | CYP2A6 (0.54) | HTTCYP1A2TDP1HSD17B10 | |
| SCHEMBL30366335 | 0.68 | CYP2A6 (0.54) | HTTCYP1A2TDP1HSD17B10 | |
| SCHEMBL11471575 | 0.67 | CYP1A2 (0.46) | KMT2AHPGDNPSR1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853400-A | IMIDAZOLE OR TRIAZOLE SUBSTITUTED INDAZOLE; | SCHERING AGROCHEMICALS LIMITED (GB) | 1989-08-01 | — | — | US | disclosed |
| US-4772613-A | Fungicides | SCHERING AGROCHEMICALS LTD. (GB) | 1988-09-20 | — | — | US | disclosed |