Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366335 | 1.00 | CYP2A6 (0.54) | CYP2A6CYP1A2ALDH1A1HSD17B10HIF1A | |
| SCHEMBL8781397 | 0.82 | HSD17B10 (0.54) | CYP2A6CYP1A2ALDH1A1HSD17B10HIF1A | |
| SCHEMBL24066459 | 0.79 | CYP2A6 (0.50) | CYP2A6CYP1A2ALDH1A1HSD17B10HIF1A | |
| SCHEMBL9730016 | 0.78 | CYP2A6 (0.52) | CYP2A6CYP1A2ALDH1A1HSD17B10HIF1A | |
| SCHEMBL30494614 | 0.77 | ALDH1A1 (0.55) | CYP2A6CYP1A2ALDH1A1HSD17B10HIF1A | |
| SCHEMBL38658983 | 0.77 | TP53 (0.50) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL29726792 | 0.77 | TP53 (0.50) | CYP2A6CYP1A2ALDH1A1HSD17B10TSHR | |
| SCHEMBL1922076 | 0.77 | ALDH1A1 (0.55) | CYP2A6CYP1A2ALDH1A1HSD17B10HIF1A | |
| SCHEMBL8847375 | 0.77 | TDP1 (0.39) | CYP2A6CYP1A2ALDH1A1HIF1AL3MBTL1 | |
| SCHEMBL4767088 | 0.76 | CYP2A6 (0.44) | CYP2A6CYP1A2ALDH1A1HSD17B10HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107722274-A | A kind of preparation method of melt-blown polyphenylene sulfide | 天津工业大学 | 2018-02-23 | — | — | CN | claimed |
| EP-0585887-A2 | Activated metathesis catalyst system | NIPPON ZEON CO., LTD. (JP) | 1994-03-09 | — | — | EP | claimed |
| US-4435222-A | HALOGENATED NAPHTHALENES AND BIPHENYLS FOLLOWED BY ALUMUNUM HALIDES | PHILLIPS PETROLEUM COMPANY (US) | 1984-03-06 | — | — | US | claimed |
| US-4286969-A | Hydrocarbon fuel additive | BWM CORPORATION (US) | 1981-09-01 | — | — | US | claimed |
| US-20240208912-A1 | MTA-Cooperative PRMT5 Inhibitors | MIRATI THERAPEUTICS INC (US) | 2024-06-27 | — | — | US | disclosed |
| US-20240208912-A1 | MTA-Cooperative PRMT5 Inhibitors | MIRATI THERAPEUTICS INC (US) | 2024-06-27 | — | — | US | disclosed |
| EP-4304720-A1 | MTA-COOPERATIVE PRMT5 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| CN-115991815-A | Halogenated modified prepared photoresist resin material and preparation method thereof | 中国科学院长春应用化学研究所 | 2023-04-21 | — | — | CN | disclosed |
| WO-2022192745-A1 | MTA-COOPERATIVE PRMT5 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-09-15 | — | — | WO | disclosed |
| EP-3564245-A1 | NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR | Osaka University (JP) | 2019-11-06 | — | — | EP | disclosed |
| WO-2018123207-A1 | NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR | 国立大学法人大阪大学 | 2018-07-05 | — | — | WO | disclosed |
| CN-107722274-A | A kind of preparation method of melt-blown polyphenylene sulfide | 天津工业大学 | 2018-02-23 | — | — | CN | disclosed |
| CN-87102669-A | Fiberboard and manufacture method thereof | — | 1987-12-30 | — | — | CN | disclosed |
| US-4435222-A | HALOGENATED NAPHTHALENES AND BIPHENYLS FOLLOWED BY ALUMUNUM HALIDES | PHILLIPS PETROLEUM COMPANY (US) | 1984-03-06 | — | — | US | disclosed |
| EP-0001096-B1 | FLAME RETARDANT POLYCARBONATE BLENDS | Mobay Chemical Corporation (US) | 1982-04-14 | — | — | EP | disclosed |
| EP-0040863-A1 | Flame-retardant polycarbonate polyblends | Mobay Chemical Corporation (US) | 1981-12-02 | — | — | EP | disclosed |
| US-4289501-A | Hydrocarbon fuel additive | BWM CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |
| US-4286969-A | Hydrocarbon fuel additive | BWM CORPORATION (US) | 1981-09-01 | — | — | US | disclosed |
| US-4174359-A | HALOGEN COMPOUND | MOBAY CHEMICAL CORPORATION (US) | 1979-11-13 | — | — | US | disclosed |
| EP-0001096-A2 | Flame retardant polycarbonate blends | Mobay Chemical Corporation (US) | 1979-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208912-A1 | MTA-Cooperative PRMT5 Inhibitors | PRMT1, PRMT5, PRMT6 | CYP2A6 4345/4885CYP1A2 4055/4885ALDH1A1 3367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.