SCHEMBL30366335

SCHEMBL30366335

Clc1cc(Cl)c2ccccc2c1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.54
CYP1A2 P05177 2/20 0.54
ALDH1A1 P00352 4/20 0.44
HSD17B10 Q99714 2/20 0.44
HIF1A Q16665 1/20 0.44
CYP1B1 Q16678 1/20 0.44
L3MBTL1 Q9Y468 4/20 0.43
MAPT P10636 2/20 0.41
HTT P42858 1/20 0.41
CCR1 P32246 1/20 0.41
CCR8 P51685 1/20 0.41
TRPM4 Q8TD43 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
AHR P35869 1/20 0.38
HTR2A P28223 1/20 0.38
NQO2 P16083 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5024019 1.00 CYP2A6 (0.54) CYP2A6CYP1A2ALDH1A1HSD17B10HIF1A
SCHEMBL8781397 0.82 HSD17B10 (0.54) CYP2A6CYP1A2ALDH1A1HSD17B10HIF1A
SCHEMBL24066459 0.79 CYP2A6 (0.50) CYP2A6CYP1A2ALDH1A1HSD17B10HIF1A
SCHEMBL9730016 0.78 CYP2A6 (0.52) CYP2A6CYP1A2ALDH1A1HSD17B10HIF1A
SCHEMBL30494614 0.77 ALDH1A1 (0.55) CYP2A6CYP1A2ALDH1A1HSD17B10HIF1A
SCHEMBL38658983 0.77 TP53 (0.50) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
SCHEMBL29726792 0.77 TP53 (0.50) CYP2A6CYP1A2ALDH1A1HSD17B10TSHR
SCHEMBL1922076 0.77 ALDH1A1 (0.55) CYP2A6CYP1A2ALDH1A1HSD17B10HIF1A
SCHEMBL8847375 0.77 TDP1 (0.39) CYP2A6CYP1A2ALDH1A1HIF1AL3MBTL1
SCHEMBL4767088 0.76 CYP2A6 (0.44) CYP2A6CYP1A2ALDH1A1HSD17B10HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688911-A1 MACRO-CYCLIC POLYESTER OLIGOMERS PRODUCED DIRECTLY FROM DIOLS AND AROMATIC DICARBOXYLIC ACIDS, AND RELATED METHODS JM Mihalich LLC (US) 2026-02-11 EP disclosed
CN-115991815-B Halogenated modified prepared photoresist resin material and preparation method thereof 中国科学院长春应用化学研究所 2025-03-07 CN disclosed
WO-2024205947-A1 MACRO-CYCLIC POLYESTER OLIGOMERS PRODUCED DIRECTLY FROM DIOLS AND AROMATIC DICARBOXYLIC ACIDS, AND RELATED METHODS JM MIHALICH LLC (US) 2024-10-03 WO disclosed
CN-115991815-A Halogenated modified prepared photoresist resin material and preparation method thereof 中国科学院长春应用化学研究所 2023-04-21 CN disclosed