Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | PMM2 | O15305 | 1/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYBB | P04839 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10561666 | 0.90 | SMN1; SMN2 (0.53) | MAPK1SMN1; SMN2PIM1KDM4EALDH1A1 | |
| SCHEMBL10563337 | 0.78 | SMN1; SMN2 (0.46) | MAPK1SMN1; SMN2PIM1KDM4ENPSR1 | |
| SCHEMBL30160665 | 0.77 | MAPK1 (0.53) | MAPK1SMN1; SMN2PIM1PGRKDM4E | |
| SCHEMBL28513461 | 0.77 | MAPK1 (0.53) | MAPK1SMN1; SMN2PIM1PGRKDM4E | |
| SCHEMBL16386794 | 0.77 | MAPK1 (0.49) | MAPK1SMN1; SMN2PIM1PGRKDM4E | |
| SCHEMBL19373335 | 0.76 | MAPK1 (0.52) | MAPK1SMN1; SMN2PGRKDM4EALDH1A1 | |
| SCHEMBL10562818 | 0.76 | KDM4E (0.58) | MAPK1SMN1; SMN2PIM1KDM4EPOLB | |
| SCHEMBL17936604 | 0.76 | MAPK1 (0.47) | MAPK1SMN1; SMN2PIM1PGRKDM4E | |
| SCHEMBL16345944 | 0.76 | MAPK1 (0.47) | MAPK1SMN1; SMN2PIM1PGRKDM4E | |
| SCHEMBL30343594 | 0.75 | MAPK1 (0.50) | MAPK1SMN1; SMN2PIM1PGRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230072683-A1 | PYRIDO-PYRIMIDIN DERIVATIVES AND PHARMACEUTICAL COMPOSITION, FOR USE IN PREVENTING OR TREATING PI3 KINASE RELATED DISEASES, COMPRISING SAME AS ACTIVE INGREDIENT | BORYUNG PHARMACEUTICAL CO., LTD. (KR) | 2023-03-09 | — | — | US | disclosed |
| CN-104703979-B | Heterocyclic compounds and their use | 无限药品股份有限公司 | 2018-11-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230072683-A1 | PYRIDO-PYRIMIDIN DERIVATIVES AND PHARMACEUTICAL COMPOSITION, FOR USE IN PREVENTING OR TREATING PI3 KINASE RELATED DISEASES, COMPRISING SAME AS ACTIVE INGREDIENT | PIK3CA, PDXK, PIK3CD | MAPK1 352/4885SMN1; SMN2 2715/4885PIM1 649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.