Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10564624 | 1.00 | ATM (0.45) | ATMADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL10566300 | 0.98 | ADRB2 (0.43) | ATMADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL10567624 | 0.98 | ADRB2 (0.43) | ATMADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL10566298 | 0.98 | ADRB2 (0.43) | ATMADRB2ADRB1ADRB3MEN1 | |
| Oxalic Acid SCHEMBL10566243 | 0.94 | ATM (0.46) | ATMADRB2ADRB1ADRB3MEN1 | |
| Oxalic Acid SCHEMBL10566281 | 0.94 | ATM (0.46) | ATMADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL10524580 | 0.92 | ADRB2 (0.44) | ATMADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL10524588 | 0.92 | ADRB2 (0.44) | ATMADRB2ADRB1ADRB3MEN1 | |
| Oxalic Acid SCHEMBL10567216 | 0.90 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1HTTKDM4E | |
| Oxalic Acid SCHEMBL10567218 | 0.90 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843085-A | LOCAL ANESTHETICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |