Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10370980 | 0.85 | KMT2A (0.47) | KMT2AHCRTR2HCRTR1 | |
| SCHEMBL10371952 | 0.81 | KMT2A (0.43) | KMT2AHCRTR2HCRTR1NMT1ROCK2 | |
| SCHEMBL10370982 | 0.80 | SCN1A (0.44) | HRH3KMT2AMEN1 | |
| SCHEMBL10372099 | 0.78 | ROCK2 (0.41) | HRH3KMT2AHCRTR2HCRTR1PARP1 | |
| SCHEMBL28976790 | 0.76 | LMNA (0.49) | KMT2AROCK2NPSR1 | |
| SCHEMBL10371065 | 0.76 | ACHE (0.44) | — | |
| SCHEMBL3934706 | 0.75 | FFAR4 (0.48) | KMT2ANPSR1 | |
| SCHEMBL10371944 | 0.74 | MAPK1 (0.45) | MAPK1 | |
| SCHEMBL10372149 | 0.74 | KDM4E (0.47) | — | |
| SCHEMBL20147430 | 0.74 | HRH3 (0.52) | HRH3HCRTR2HCRTR1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4812565-A | ANTIHISTAMINE INTERMEDIATES | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-14 | — | — | US | disclosed |