Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4964623 | 0.82 | SLC22A12 (0.44) | ALDH1A1HPGDMAPTNPSR1HSD17B10 | |
| SCHEMBL9719712 | 0.80 | ALDH1A1 (0.42) | LMNAALDH1A1CES1CES2NAPRT | |
| SCHEMBL4967515 | 0.78 | SIRT1 (0.39) | ALDH1A1TSHRHPGDMAPTHSD17B10 | |
| SCHEMBL4202728 | 0.74 | KMT2A (0.44) | LMNAALDH1A1TSHRHPGDMAPT | |
| SCHEMBL11622286 | 0.73 | AKR1C1 (0.41) | LMNAALDH1A1CES1CES2TSHR | |
| SCHEMBL3058072 | 0.73 | SLC22A12 (0.48) | NPSR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28198972 | 0.72 | MAPT (0.39) | LMNAALDH1A1CES1CES2TSHR | |
| SCHEMBL11622294 | 0.70 | AKR1C1 (0.39) | LMNAALDH1A1CES1CES2TSHR | |
| SCHEMBL10456685 | 0.69 | FFAR1 (0.39) | LMNAALDH1A1HPGDMAPTHTT | |
| SCHEMBL11341980 | 0.69 | CES1 (0.46) | LMNAALDH1A1CES1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4829075-A | ANTIPROTOZOA, BACTERICIDES, YEASTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-09 | — | — | US | disclosed |
| EP-0237916-A2 | 1,1-Disubstituted cyclopropane derivatives, processes for their preparation and their use as antimycotics or as intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | disclosed |