SCHEMBL9719712

SCHEMBL9719712

CC(=O)C1(Sc2ccccc2)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
HPGD P15428 1/20 0.42
MTNR1A P48039 4/20 0.38
MTNR1B P49286 4/20 0.38
OPRM1 P35372 1/20 0.38
OPRL1 P41146 1/20 0.38
FFAR1 O14842 1/20 0.38
HSD17B10 Q99714 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPK1 P28482 2/20 0.36
NPC1 O15118 1/20 0.36
CASP1 P29466 1/20 0.36
RAB9A P51151 1/20 0.36
CASP7 P55210 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
AKR1C1 Q04828 1/20 0.35
USP2 O75604 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4964623 0.85 SLC22A12 (0.44) ALDH1A1HPGDMTNR1AMTNR1BFFAR1
SCHEMBL4967515 0.82 SIRT1 (0.39) ALDH1A1HPGDFFAR1HSD17B10MEN1
SCHEMBL4202728 0.81 KMT2A (0.44) ALDH1A1HPGDOPRM1HSD17B10MEN1
SCHEMBL10565002 0.80 LMNA (0.40) ALDH1A1HPGDFFAR1HSD17B10MEN1
SCHEMBL3058072 0.76 SLC22A12 (0.48) MEN1KMT2ASMN1; SMN2AKR1C1HSD11B1
SCHEMBL2951655 0.73 CYP3A4 (0.43) ALDH1A1MEN1KMT2AAKR1C1
SCHEMBL4966169 0.72 SLC22A12 (0.43) ALDH1A1HPGDMEN1KMT2ASMN1; SMN2
SCHEMBL10456685 0.72 FFAR1 (0.39) ALDH1A1HPGDMTNR1AMTNR1BFFAR1
SCHEMBL11313214 0.70 MTNR1A (0.38) ALDH1A1HPGDMTNR1AMTNR1BHSD17B10
SCHEMBL9172518 0.69 FFAR1 (0.46) ALDH1A1HPGDMTNR1AMTNR1BFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5079374-A Cyclopropyl-oxirane compounds as intermediates BAYER AKTIENGESELLSCHAFT (DE) 1992-01-07 US disclosed
US-4983208-A Plant diseases, cereal crops BAYER AKTIENGESELLSCHAFT (DE) 1991-01-08 US disclosed
EP-0298332-B1 HYDROXY-ALKYLAZOLYL DERIVATIVES BAYER AG (DE) 1990-11-28 EP disclosed
US-4925482-A Fungicidal and plant growth-regulating hydroxyalkyl-azolyl derivatives BAYER AKTIENGESELLSCHAFT (DE) 1990-05-15 US disclosed
US-4925865-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1990-05-15 US disclosed
EP-0298332-A1 Hydroxy-alkylazolyl derivatives BAYER AG (DE) 1989-01-11 EP disclosed