Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL10569526 | 0.85 | CA2 (0.74) | CA2GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL38598 | 0.77 | CA2 (1.00) | CA2GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL23964437 | 0.76 | ALDH1A1 (0.50) | CA2GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL8607311 | 0.75 | RXFP1 (0.52) | CA2HPGDGAA | |
| SCHEMBL29614734 | 0.74 | CA2 (0.94) | CA2GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL29189109 | 0.74 | CA2 (0.94) | CA2GABRA1GABRB2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7076174 | 0.74 | CA2 (0.94) | CA2GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL31622310 | 0.74 | CA2 (0.94) | CA2GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL22444875 | 0.74 | CA2 (0.94) | CA2GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL29978072 | 0.74 | CA2 (0.94) | CA2GABRA1GABRB2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4798678-A | HINDERED PHENOL, PIPERAZINE | TEXACO INC. (US) | 1989-01-17 | — | — | US | disclosed |