Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10567011 | 1.00 | ALDH1A1 (0.44) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL9585609 | 0.88 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL9585614 | 0.88 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL9585682 | 0.72 | ALDH1A1 (0.50) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL10759727 | 0.70 | ALDH1A1 (0.51) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL6058822 | 0.69 | TSHR (0.67) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL6058824 | 0.69 | TSHR (0.61) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL1498218 | 0.68 | TSHR (0.59) | ALDH1A1LMNATSHRL3MBTL1ESR1 | |
| SCHEMBL829756 | 0.66 | ALDH1A1 (0.69) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL28651663 | 0.65 | TSHR (0.52) | ALDH1A1LMNATSHRL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863503-A | THIOPHENE DERIVATIVES, INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-05 | — | — | US | disclosed |