Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10759727 | 0.75 | ALDH1A1 (0.51) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL2852275 | 0.75 | CYP2C9 (0.50) | ALDH1A1TSHRTDP1KDM4EHSD17B10 | |
| SCHEMBL12233265 | 0.74 | TSHR (0.52) | ALDH1A1LMNATSHRL3MBTL1ESR1 | |
| SCHEMBL22528255 | 0.72 | AKR1B1 (0.46) | LMNATSHRTDP1KDM4EHSD17B10 | |
| SCHEMBL10567011 | 0.72 | ALDH1A1 (0.44) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL10567013 | 0.72 | ALDH1A1 (0.44) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL6058822 | 0.71 | TSHR (0.67) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL6058824 | 0.71 | TSHR (0.61) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL829756 | 0.70 | ALDH1A1 (0.69) | ALDH1A1LMNATSHRTDP1L3MBTL1 | |
| SCHEMBL1498218 | 0.69 | TSHR (0.59) | ALDH1A1LMNATSHRL3MBTL1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258360-A | Fungicides, insecticides or plant growth regulators | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-11-02 | — | — | US | disclosed |
| US-5160364-A | Thiophene substituted acrylic derivatives; insecticides, plant growth regulators | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-11-03 | — | — | US | disclosed |
| US-5073184-A | Agricultural fungicides, insecticides, plant growth regulators | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-12-17 | — | — | US | disclosed |
| US-5053073-A | THIOPHENE DERIVATIVES USEFUL AS FUNGICIDAL, INSECTICIDAL OR PLANT GROWTH REGULATING AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | disclosed |
| EP-0243014-B1 | FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-03-06 | — | — | EP | disclosed |
| US-4863503-A | THIOPHENE DERIVATIVES, INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-05 | — | — | US | disclosed |
| EP-0243014-A1 | Fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-28 | — | — | EP | disclosed |