Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 15/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.37 |
| ▸ | GABRP | O00591 | 3/20 | 0.36 |
| ▸ | GABRD | O14764 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.36 |
| ▸ | GABRE | P78334 | 3/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10563548 | 0.92 | BACE1 (0.41) | BACE1MEN1KMT2AGABRB3GABRA2 | |
| SCHEMBL10563234 | 0.83 | GABRB3 (0.38) | BACE1CYP3A4GABRB3GABRA2GABRB2 | |
| SCHEMBL7713328 | 0.81 | BACE1 (0.41) | BACE1CYP3A4GABRB3GABRA2GABRB2 | |
| SCHEMBL7707255 | 0.81 | BACE1 (0.40) | BACE1CYP3A4GABRB3GABRA2GABRB2 | |
| SCHEMBL7713349 | 0.80 | GABRB3 (0.45) | BACE1MEN1KMT2AGABRB3GABRA2 | |
| SCHEMBL10563898 | 0.76 | GABRP (0.50) | CYP3A4GABRB3GABRA2GABRB2GABRP | |
| SCHEMBL10564281 | 0.76 | GABRB3 (0.43) | BACE1CYP3A4GABRB3GABRA2GABRB2 | |
| SCHEMBL7713491 | 0.76 | BACE1 (0.41) | BACE1CYP3A4GABRB3GABRA2GABRB2 | |
| SCHEMBL9010510 | 0.76 | GABRB3 (0.40) | BACE1MEN1KMT2AGABRB3GABRA2 | |
| SCHEMBL10568665 | 0.74 | GABRB3 (0.39) | BACE1CYP3A4GABRB3GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826867-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-02 | — | — | US | disclosed |