Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 16/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 13/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 13/20 | 0.39 |
| ▸ | GABRP | O00591 | 9/20 | 0.39 |
| ▸ | GABRD | O14764 | 9/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 9/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 9/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 9/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 9/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 9/20 | 0.39 |
| ▸ | GABRE | P78334 | 9/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 9/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 9/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 9/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 9/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10563898 | 0.84 | GABRP (0.50) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10564281 | 0.84 | GABRB3 (0.43) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10563548 | 0.76 | BACE1 (0.41) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10563234 | 0.76 | GABRB3 (0.38) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7713150 | 0.75 | GABRB3 (0.41) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10548077 | 0.75 | TDP1 (0.44) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7707464 | 0.75 | GABRA2 (0.50) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10567110 | 0.74 | BACE1 (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7713328 | 0.72 | BACE1 (0.41) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7707491 | 0.71 | GABRP (0.52) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826867-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-02 | — | — | US | disclosed |
| EP-0257479-A1 | Substituted 1-aryl-3-tert.-butyl pyrazoles | BAYER AG (DE) | 1988-03-02 | — | — | EP | disclosed |