Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18809216 | 0.86 | SMN1; SMN2 (0.41) | CES2CES1MAOAMAOBCA1 | |
| SCHEMBL18400815 | 0.83 | MAOA (0.40) | CES2CES1MAOAMAOBCA1 | |
| SCHEMBL19262505 | 0.81 | SMN1; SMN2 (0.38) | CES2CES1MAOAMAOBCA1 | |
| SCHEMBL21013602 | 0.80 | MAOA (0.45) | CES2CES1MAOAMAOBCA1 | |
| SCHEMBL18937205 | 0.80 | MAOA (0.38) | CES2CES1MAOAMAOBPTPN1 | |
| SCHEMBL13984127 | 0.78 | MAOA (0.37) | CES2CES1MAOAMAOBNPC1 | |
| SCHEMBL18809600 | 0.75 | LMNA (0.38) | MAOAMAOBLMNAPTBP1SMN1; SMN2 | |
| SCHEMBL18432036 | 0.75 | LMNA (0.38) | CES2CES1MAOAMAOBNPC1 | |
| SCHEMBL18808881 | 0.75 | SMN1; SMN2 (0.36) | CES2CES1MAOAMAOBLMNA | |
| SCHEMBL18809051 | 0.75 | MAOB (0.35) | MAOAMAOBLMNAPTBP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876275-A | 3,4-dihydro-2H-pyrans useful as pesticides | BASF AKTIENGESELLSCHAFT (DE) | 1989-10-24 | — | — | US | disclosed |