Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18400815 | 0.81 | MAOA (0.40) | MAOAMAOBLMNAHTR7PTBP1 | |
| SCHEMBL10567241 | 0.80 | CES2 (0.46) | MAOAMAOBLMNAPTBP1SMN1; SMN2 | |
| SCHEMBL18809216 | 0.76 | SMN1; SMN2 (0.41) | MAOAMAOBLMNAPTBP1SMN1; SMN2 | |
| SCHEMBL3596705 | 0.75 | MAPT (0.47) | MAOAMAOBLMNAHTR7PTBP1 | |
| SCHEMBL18809600 | 0.74 | LMNA (0.38) | MAOAMAOBLMNAHTR7PTBP1 | |
| SCHEMBL18809492 | 0.74 | LMNA (0.41) | MAOAMAOBLMNAHTR7PTBP1 | |
| SCHEMBL18809051 | 0.74 | MAOB (0.35) | MAOAMAOBLMNAHTR7PTBP1 | |
| SCHEMBL24222565 | 0.73 | MAOA (0.40) | MAOAMAOBLMNAHTR7PTBP1 | |
| SCHEMBL19262505 | 0.72 | SMN1; SMN2 (0.38) | MAOAMAOBLMNAPTBP1SMN1; SMN2 | |
| SCHEMBL21169035 | 0.71 | MAOB (0.37) | MAOAMAOBLMNAHTR7PTBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560976-B9 | FUROPYRIDINE COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2017-06-07 | — | — | EP | disclosed |