SCHEMBL10567294

SCHEMBL10567294

O=C(O)CCSCCCCCCSCCC(=O)O

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.78
HSD17B10 Q99714 2/20 0.78
KMT2A Q03164 1/20 0.78
TDP1 Q9NUW8 1/20 0.78
BHMT Q93088 3/20 0.59
TSHR P16473 3/20 0.55
NFKB1 P19838 1/20 0.50
PMP22 Q01453 1/20 0.50
PLA2G4B P0C869 1/20 0.49
GMNN O75496 1/20 0.48
TP53 P04637 1/20 0.48
POLB P06746 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
CYP2C9 P11712 1/20 0.48
BLM P54132 1/20 0.48
SLC22A6 Q4U2R8 1/20 0.45
CYP2C19 P33261 1/20 0.45
ALKBH5 Q6P6C2 1/20 0.42
SUCNR1 Q9BXA5 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6536792 0.92 LMNA (0.74) LMNAHSD17B10KMT2ATDP1BHMT
SCHEMBL23393577 0.91 LMNA (0.64) LMNAHSD17B10KMT2ATDP1BHMT
SCHEMBL9264322 0.91 LMNA (0.64) LMNAHSD17B10KMT2ATDP1BHMT
SCHEMBL9260266 0.91 LMNA (0.64) LMNAHSD17B10KMT2ATDP1BHMT
SCHEMBL6866613 0.89 LMNA (0.78) LMNAHSD17B10KMT2ATDP1BHMT
SCHEMBL5168783 0.89 TSHR (0.67) LMNAHSD17B10KMT2ATDP1BHMT
SCHEMBL7692824 0.89 TSHR (0.67) LMNAHSD17B10KMT2ATDP1BHMT
SCHEMBL7693275 0.89 TSHR (0.67) LMNAHSD17B10KMT2ATDP1BHMT
SCHEMBL20475058 0.89 TSHR (0.67) LMNAHSD17B10KMT2ATDP1BHMT
SCHEMBL14271423 0.89 LMNA (0.78) LMNAHSD17B10KMT2ATDP1BHMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4863982-A HEAT, LIGHT AND OXIDATION STABILIZERS CIBA-GEIGY CORPORATION (US) 1989-09-05 US disclosed
US-4699939-A OXIDATION RESISTANCE, PHOTOSTABILITY CIBA-GEIGY CORPORATION (US) 1987-10-13 US disclosed