Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3085648 | 0.79 | ALDH1A1 (0.46) | HPGDTSHRGAAALDH1A1MAPT | |
| SCHEMBL3085646 | 0.79 | ALDH1A1 (0.46) | HPGDTSHRGAAALDH1A1MAPT | |
| SCHEMBL6450098 | 0.78 | ERN1 (0.59) | HPGDTSHRGAAALDH1A1MAPT | |
| SCHEMBL6450101 | 0.78 | ERN1 (0.59) | HPGDTSHRGAAALDH1A1MAPT | |
| SCHEMBL28374737 | 0.75 | PTGS2 (0.38) | HPGDTSHRGAAALDH1A1MAPT | |
| SCHEMBL4808231 | 0.72 | ERN1 (0.57) | HPGDTSHRGAAALDH1A1MAPT | |
| SCHEMBL17064025 | 0.72 | ALDH1A1 (0.46) | HPGDGAAALDH1A1MAPTMEN1 | |
| SCHEMBL17064023 | 0.72 | ALDH1A1 (0.46) | HPGDGAAALDH1A1MAPTMEN1 | |
| SCHEMBL28153812 | 0.72 | ALDH1A1 (0.42) | HPGDTSHRALDH1A1MAPTERN1 | |
| SCHEMBL19216538 | 0.72 | ALDH1A1 (0.42) | HPGDTSHRALDH1A1MAPTERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810811-A | CHEMICAL INTERMEDIATES | SMITHKLINE BECKMAN CORPORATION (US) | 1989-03-07 | — | — | US | disclosed |
| US-4707488-A | HYPOTENSIVE AGENTS | SMITHKLINE BECKMAN CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |