Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23925994 | 0.83 | TSHR (0.41) | ALDH1A1KDM4EHSD17B10MAPTPDK2 | |
| SCHEMBL23250280 | 0.82 | CXCR2 (0.35) | HSD11B1CXCR2CXCR1NOTUM | |
| SCHEMBL29863304 | 0.82 | CXCR2 (0.35) | HSD11B1CXCR2CXCR1NOTUM | |
| SCHEMBL17205759 | 0.80 | KDM4E (0.37) | HSD11B1CXCR2CXCR1ALDH1A1HPGD | |
| SCHEMBL27351302 | 0.77 | HSD11B1 (0.56) | HSD11B1CXCR2CXCR1ALDH1A1HPGD | |
| SCHEMBL1748180 | 0.77 | HSD11B1 (0.56) | HSD11B1CXCR2CXCR1ALDH1A1HPGD | |
| SCHEMBL8434832 | 0.77 | HSD11B1 (0.44) | HSD11B1CXCR2CXCR1ALDH1A1HPGD | |
| SCHEMBL19330864 | 0.77 | CFTR (0.38) | HSD11B1CXCR2CXCR1ALDH1A1HPGD | |
| SCHEMBL9275010 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10CYP2C19NOTUM | |
| SCHEMBL7318290 | 0.75 | MAPT (0.51) | HSD11B1CXCR2CXCR1CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011008725-A2 | METAL-CATALYZED CARBON-FLUORINE BOND FORMATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-01-20 | — | — | WO | disclosed |
| US-20110015401-A1 | Metal-Catalyzed Carbon-Fluorine Bond Formation | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-01-20 | — | — | US | disclosed |
| WO-2011008618-A1 | METAL-CATALYZED CARBON-FLUORINE BOND FORMATION | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015401-A1 | Metal-Catalyzed Carbon-Fluorine Bond Formation | FLI1, VGF, GMFG | HSD11B1 3639/4885CXCR2 2378/4885CXCR1 2052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.