Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372313 | 0.79 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL10565445 | 0.77 | MAPT (0.47) | SMN1; SMN2POLBTDP1MAPTMEN1 | |
| SCHEMBL11706189 | 0.77 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL11559997 | 0.76 | MAPT (0.51) | POLBMAPTMEN1KMT2ACA1 | |
| SCHEMBL10567054 | 0.76 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL11555602 | 0.75 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL11688824 | 0.74 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8779354 | 0.71 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL11864325 | 0.70 | CYP2C19 (0.44) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL11703246 | 0.70 | ALDH1A1 (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876044-A | PESTICIDES, HERBICIDES | AIR PRODUCTS AND CHEMICALS, INC. | 1989-10-24 | — | — | US | disclosed |
| US-4165229-A | SUBSTITUTED THIADIAZOL-2-YLUREA | ELI LILLY AND COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-3972706-A | SUBSTITUTED THIADIAZOL-2-YL-UREAS | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | disclosed |