Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAPDH | P04406 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11689676 | 0.80 | TP53 (0.49) | ALDH1A1KDM4EHSD17B10MEN1POLB | |
| SCHEMBL11690673 | 0.77 | CA1 (0.43) | MEN1POLBBLMKMT2ATDP1 | |
| SCHEMBL11687601 | 0.77 | SMN1; SMN2 (0.52) | ALDH1A1TSHRCYP2C9KDM4EMEN1 | |
| SCHEMBL11707860 | 0.77 | NPSR1 (0.54) | ALDH1A1TSHRNPSR1CYP2C9GLS | |
| SCHEMBL11634995 | 0.76 | POLB (0.51) | TSHRNPSR1HSD17B10MEN1POLB | |
| SCHEMBL11706516 | 0.76 | NPSR1 (0.56) | ALDH1A1TSHRNPSR1CYP2C9GLS | |
| SCHEMBL11669564 | 0.75 | ALDH1A1 (0.51) | ALDH1A1CYP2C9HSD17B10MEN1POLB | |
| SCHEMBL11670623 | 0.75 | ALDH1A1 (0.54) | ALDH1A1TSHRNPSR1HSD17B10MEN1 | |
| SCHEMBL11669924 | 0.75 | ALDH1A1 (0.54) | ALDH1A1TSHRNPSR1HSD17B10MEN1 | |
| SCHEMBL11856846 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRNPSR1CYP2C9GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4006009-A | 1-Thiadiazolyl-6-acyloxytetrahydropyrimidinone herbicides | VELSICOL CHEMICAL CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |